AP1S1

Gene Symbol AP1S1
Entrez Gene 1174
Alt Symbol AP19, CLAPS1, EKV3, MEDNIK, SIGMA1A
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 1, sigma 1 subunit
Other Description AP-1 complex subunit sigma-1A|HA1 19 kDa subunit|adapter-related protein complex 1 sigma-1A subunit|adaptor protein complex AP-1 subunit sigma-1A|adaptor-related protein complex 1 subunit sigma-1A|clathrin assembly protein complex 1 sigma-1A small chain|clathrin coat assembly protein AP19|clathrin-associated/assembly/adaptor protein, small 1 (19kD)|golgi adaptor HA1/AP1 adaptin sigma-1A subunit|sigma1A subunit of AP-1 clathrin adaptor complex|sigma1A-adaptin
Swissprots B2R5D8 Q9UDW9 Q9BTN4 Q53YA7 Q00382 P82267 P61966
Accessions AAD45829 EAW50198 EAW50199 EAW50200 P61966 AB015319 BAA33391 AK312151 BAG35085 BC003561 AAH03561 BI597121 BI598615 BI857465 BT006779 AAP35425 NM_001283 NP_001274 NM_057089
Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. {ECO:0000269|PubMed:9733768}.
Subcellular Location Golgi apparatus {ECO:0000269|PubMed:9733768}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:9733768}; Peripheral membrane protein {ECO:0000269|PubMed:9733768}; Cytoplasmic side {ECO:0000269|PubMed:9733768}. Membrane, clathrin-coated pit {ECO:0000269|PubMed:9733768}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:9733768}.
Top Pathways Lysosome

AP1S1 CRISPR/Cas9 KO Plasmid (h) - sc-408436 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 HDR Plasmid (h) - sc-408436-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 Double Nickase Plasmid (h) - sc-408436-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 Double Nickase Plasmid (h2) - sc-408436-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 CRISPR Activation Plasmid (h) - sc-408436-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 CRISPR Activation Plasmid (h2) - sc-408436-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 Lentiviral Activation Particles (h) - sc-408436-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 Lentiviral Activation Particles (h2) - sc-408436-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AP1S1 siRNA (h) - sc-60182 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AP1S1 shRNA Plasmid (h) - sc-60182-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AP1S1 shRNA (h) Lentiviral Particles - sc-60182-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AP1S1 RNAi - H00001174-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU078061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3284 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3284 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06315 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06315

AP1S1 siRNA (Human) - CRH0837 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AP1S1 RNAi - H00001174-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AP1S1 - MBS8201691 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AP1S1 (NM_001283.3) - SHH237786 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AP1S1(NM_001283.3) - SHG062975 from Creative biogene

Category siRNA
Species Reactivities Human

AP1S1 shRNA Plasmid (Human) - CHH0837 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AP1S1 miRNA 3'UTR clone - MiUTR1H-00436 from Creative biogene

Species Reactivities Human
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