SIX5

Gene Symbol SIX5
Entrez Gene 147912
Alt Symbol BOR2, DMAHP
Species Human
Gene Type protein-coding
Description SIX homeobox 5
Other Description DM locus-associated homeodomain protein|dystrophia myotonica-associated homeodomain protein|homeobox protein SIX5|sine oculis homeobox homolog 5
Swissprots Q8N196
Accessions EAW57379 Q8N196 AK074826 AL540911 BC033204 AAH33204 BC084563 BC156208 AAI56209 BC156983 AAI56984 BU859227 NM_175875 NP_787071
Function Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'- TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12500905}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12500905}.
Tissue Specificity Expressed in adult but not in fetal eyes. Found in corneal epithelium and endothelium, lens epithelium, ciliary body epithelia, cellular layers of the retina and the sclera. {ECO:0000269|PubMed:9949207}.

Six5 CRISPR/Cas9 KO Plasmid (h) - sc-410513 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 HDR Plasmid (h) - sc-410513-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 Double Nickase Plasmid (h) - sc-410513-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 Double Nickase Plasmid (h2) - sc-410513-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 CRISPR Activation Plasmid (h) - sc-410513-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 CRISPR Activation Plasmid (h2) - sc-410513-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 Lentiviral Activation Particles (h) - sc-410513-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 Lentiviral Activation Particles (h2) - sc-410513-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Six5 siRNA (h) - sc-63034 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Six5 shRNA Plasmid (h) - sc-63034-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Six5 shRNA (h) Lentiviral Particles - sc-63034-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19371 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19371 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SIX5 siRNA (Human) - CRJ5549 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Six5 RNAi - H00147912-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SIX5 - MBS8238291 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SIX5 (NM_175875.4) - SHH407884 from Creative biogene

Category siRNA
Species Reactivities Human

Human SIX5 siRNA - orb276050 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIX5 shRNA Plasmid (Human) - CHJ5549 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SIX5 miRNA 3'UTR clone - MiUTR3H-03777 from Creative biogene

Species Reactivities Human
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