SIX5

Gene Symbol SIX5
Entrez Gene 147912
Alt Symbol BOR2, DMAHP
Species Human
Gene Type protein-coding
Description SIX homeobox 5
Other Description DM locus-associated homeodomain protein|dystrophia myotonica-associated homeodomain protein|homeobox protein SIX5|sine oculis homeobox homolog 5
Swissprots Q8N196
Accessions EAW57379 Q8N196 AK074826 AL540911 BC033204 AAH33204 BC084563 BC156208 AAI56209 BC156983 AAI56984 BU859227 NM_175875 NP_787071
Function Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'- TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12500905}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12500905}.
Tissue Specificity Expressed in adult but not in fetal eyes. Found in corneal epithelium and endothelium, lens epithelium, ciliary body epithelia, cellular layers of the retina and the sclera. {ECO:0000269|PubMed:9949207}.

Six5 (H-300) - sc-134925 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Six5 (H-300): sc-134925. Western blot analysis of Six5 expression in K-562 (A) and Jurkat (B) whole cell lysates.

Six5 (K-20) - sc-55706 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Six5 antibody - ab113064 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of formalin fixed and paraffin embedded Human liver tissue labelling Six5 with ab113064.

Anti-Six5 antibody - ab74071 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Six5 antibody (ab74071) at 1/500 dilutionLane 1 : extracts from K562 cellsLane 2 : extracts from K562 cells with immunizing peptide at 10 µgLysates/proteins at 20 µg per lane.

Anti-SIX5 Antibody - LS-C10192 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa257-286, AP) - LS-C240812 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa257-286, APC) - LS-C240813 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa257-286, Biotin) - LS-C240815 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa257-286, FITC) - LS-C240816 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa257-286, PE) - LS-C240817 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa257-286, Azide-free, HRP) - LS-C248164 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa264-294) - LS-C325127 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIX5 Antibody (aa201-250) - LS-C120047 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from K562 cells, using SIX5 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SIX5 Antibody (Leu237) - LS-C177463 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Six5 (L237) pAb in extracts from K562 cells.

Anti-SIX5 Antibody (aa257-286) - LS-C161108 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SIX5 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Six5 Antibody - NBP1-85009 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Six5 Antibody [NBP1-85009] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Six5 Antibody - NBP1-01007 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Six5 Antibody [NBP1-01007] - Western blot (WB) analysis of Six5 (L237) antibody in extracts from K562 cells

Anti-SIX5 antibody produced in rabbit - SAB4500528 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SIX5: <B>Cat. No. SAB4500528</B>: Immunoblotting analysis of extracts from K562 cells, using Anti-SIX5 antibody. The lane on the left was treated with the Anti-SIX5 antibody. The lane on the right (negative control) was treated with both Anti-SIX5 antibody and the synthesized immunogen peptide.

ANTI-SIX5 (CENTER) antibody produced in rabbit - SAB1307236 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SIX5 (Center): <B>Cat. No. SAB1307236</B>: SIX5 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35 μg/lane).

SIX5-Antibody-Center - AP12740c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SIX5 Antibody (Center) (Cat. #AP12740c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SIX5 antibody detected the SIX5 protein (arrow).

SIX5 Antibody - middle region (OAAB09022) - OAAB09022 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SIX5 Antibody (OAAF03772) - OAAF03772 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SIX5 antibody - orb186151 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

SIX5 Antibody - abx026987 from Abbexa

Host Rabbit
Clonality Polyclonal

SIX5 Antibody - abx014539 from Abbexa

Host Rabbit
Clonality Polyclonal
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