| Gene Symbol |
DUSP7
|
| Entrez Gene |
1849
|
| Alt Symbol |
MKPX, PYST2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dual specificity phosphatase 7
|
| Other Description |
dual specificity protein phosphatase 7|dual specificity protein phosphatase PYST2|dual-specificity phosphatase-7
|
| Swissprots |
Q16829 Q8NFJ0 Q2M3J7
|
| Accessions |
EAW65184 Q16829 AF508727 AAM77606 AF508728 AL110157 BC019107 AAH19107 BC104880 AAI04881 BC104882 AAI04883 BC128064 CN429806 DN999200 X93921 CAA63814 NM_001947 NP_001938
|
| Function |
Regulates the activity of the MAP kinase family in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L although it is unclear whether this is by competing for transcription, translation or activation factors. {ECO:0000269|PubMed:14603440}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells. {ECO:0000269|PubMed:14576828}.
|
| Top Pathways |
MAPK signaling pathway
|