POMGNT1

Gene Symbol	POMGNT1
Entrez Gene	55624
Alt Symbol	GNTI.2, GnT I.2, LGMD2O, MEB, MGAT1.2, gnT-I.2
Species	Human
Gene Type	protein-coding
Description	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Other Description	UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2|protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
Swissprots	Q5VST3 Q8WZA1 Q9NYF7 Q9H9L8 Q9BV55 D3DQ16 Q9NXF9 Q5VST2
Accessions	EAX06932 EAX06933 EAX06934 EAX06935 EAX06936 Q8WZA1 AA918249 AB057356 BAB71960 AF250859 AAF71270 AK000284 BAA91053 AK022727 BAB14207 AK026430 AK055301 AK056186 AK225033 AK301923 BAH13588 AK302379 BAH13690 AK316399 BAH14770 AW818474 AY358592 AAQ88955 BC001471 AAH01471 BM999774 BQ448444 CB146374 CR749700 CAH18478 DA187331 XM_005271010 XP_005271067 XM_006710755 XP_006710818 XM_006710756 XP_006710819 XM_011541759 XP_011540061 XM_011541760 XP_011540062 XM_011541761 XP_011540063 XR_946706 NM_001243766 NP_001230695 NM_001290129 NP_001277058 NM_001290130 NP_001277059 NM_017739 NP_060209
Function	Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O- Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity. {ECO:0000269|PubMed:11709191}.
Subcellular Location	Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity	Constitutively expressed. An additional weaker band is also detected in spinal cord, lymph node, and trachea. Expressed especially in astrocytes. Also expressed in immature and mature neurons. {ECO:0000269|PubMed:11709191, ECO:0000269|PubMed:11742540}.
Top Pathways	Other types of O-glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human POMGNT1 full length protein - ab153784 from Abcam Category Protein Source HEK 293 cells Species Human

POMGNT1 Antibody Blocking Peptide - LS-E17645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human POMGNT1 Protein - H00055624-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human POMGNT1, CF - 7414-GT-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ser66-Thr660, with an N-terminal human CD33 signal sequence and a C-terminal 6-His tag

Human POMGNT1 protein - orb49615 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

POMGNT1 - H00055624-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

POMGNT1 - H00055624-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Protein O-Linked-Mannose beta -1 2-N-Acetylglucosaminyltransferase 1, POMGNT1, Human, Recombinant - 19-C671 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source HEK293 Species Human

POMGNT1 fusion protein - ag7029 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human POMGNT1 Enzyme - BP001166-C671 from Syd Labs Category Protein Prices $180.00, $528.00, $2,640.00 Sizes 10 µg, 10 µg, 1 mg Source HEK 293-derived. Species Human

Recombinant Human POMGNT1, His-tagged - POMGNT1-27934TH from Creative Biomart Category Protein Source E. coli

Recombinant Human POMGNT1, His-tagged - POMGNT1-289H from Creative Biomart Category Protein Source Baculovirus Sf 21 Insect cells Species Human

Recombinant Human Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransfer - CSB-YP855513HU CSB-EP855513HU CSB-BP855513HU CSB-MP855513HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human POMGNT1 Protein, CF - 7414-GT from R&D Systems Category Protein Prices $359.00 Sizes 10 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Ser66-Thr660, with an N-terminal human CD33 signal sequence and a C-terminal 6-His tag Species Human

POMGNT1 (transcript variant 1) - TP720707 from Acris Antibodies Category Protein Prices $139.00 Sizes 10 µg Source HEK293 cells Species Human

POMGNT1 Recombinant Protein Antigen - NBP1-82193PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

POMGNT1 Peptide, Human - M34GP12120H from Creative Peptides Category Peptide Source Synthetic. Species Human

POMGNT1 Recombinant Protein - 91-563 from ProSci Category Protein Prices $575.00 Sizes 50 µg Source Human Cells Species Human

POMGNT1, Recombinant Protein - MBS8249618 from MyBioSource Category Protein Prices $255.00, $635.00, $2,370.00 Sizes 10 µg, 50 µg, 500 µg Source Human cells Species Human

Recombinant Human POMGNT1 Protein, CF - 7414-GT from Novus Biologicals Category Protein Prices $359.00 Sizes 10 µg Species Human

Recombinant Human POMGNT1 (C-6His) - AP75306 from Signalway Antibody Category Protein Prices $349.00, $749.00, $2,289.00, $3,209.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source Human Cells Species Human

Human POMGNT1 protein - orb392308 from Biorbyt Category Protein Species Human

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