POMGNT1

Gene Symbol POMGNT1
Entrez Gene 55624
Alt Symbol GNTI.2, GnT I.2, LGMD2O, MEB, MGAT1.2, gnT-I.2
Species Human
Gene Type protein-coding
Description protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Other Description UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2|protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
Swissprots Q5VST3 Q8WZA1 Q9NYF7 Q9H9L8 Q9BV55 D3DQ16 Q9NXF9 Q5VST2
Accessions EAX06932 EAX06933 EAX06934 EAX06935 EAX06936 Q8WZA1 AA918249 AB057356 BAB71960 AF250859 AAF71270 AK000284 BAA91053 AK022727 BAB14207 AK026430 AK055301 AK056186 AK225033 AK301923 BAH13588 AK302379 BAH13690 AK316399 BAH14770 AW818474 AY358592 AAQ88955 BC001471 AAH01471 BM999774 BQ448444 CB146374 CR749700 CAH18478 DA187331 XM_005271010 XP_005271067 XM_006710755 XP_006710818 XM_006710756 XP_006710819 XM_011541759 XP_011540061 XM_011541760 XP_011540062 XM_011541761 XP_011540063 XR_946706 NM_001243766 NP_001230695 NM_001290129 NP_001277058 NM_001290130 NP_001277059 NM_017739 NP_060209
Function Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O- Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity. {ECO:0000269|PubMed:11709191}.
Subcellular Location Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Constitutively expressed. An additional weaker band is also detected in spinal cord, lymph node, and trachea. Expressed especially in astrocytes. Also expressed in immature and mature neurons. {ECO:0000269|PubMed:11709191, ECO:0000269|PubMed:11742540}.
Top Pathways Other types of O-glycan biosynthesis

POMGnT1 CRISPR/Cas9 KO Plasmid (h) - sc-407080 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 HDR Plasmid (h) - sc-407080-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 Double Nickase Plasmid (h) - sc-407080-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 Double Nickase Plasmid (h2) - sc-407080-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 CRISPR Activation Plasmid (h) - sc-407080-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 CRISPR Activation Plasmid (h2) - sc-407080-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 Lentiviral Activation Particles (h) - sc-407080-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 Lentiviral Activation Particles (h2) - sc-407080-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POMGnT1 siRNA (h) - sc-40865 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POMGnT1 shRNA Plasmid (h) - sc-40865-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POMGnT1 shRNA (h) Lentiviral Particles - sc-40865-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050881 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17147 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17147 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12206 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12206

POMGNT1 siRNA (Human) - CRJ0783 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POMGNT1 RNAi - H00055624-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human POMGNT1 (NM_017739.3) - SHH379728 from Creative biogene

Category siRNA
Species Reactivities Human

Human POMGNT1 siRNA - orb271284 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POMGNT1 shRNA Plasmid (Human) - CHJ0783 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

POMGNT1 miRNA 3'UTR clone - MiUTR3H-08749 from Creative biogene

Species Reactivities Human
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