Gene Symbol | FEZF1 |
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Entrez Gene | 389549 |
Alt Symbol | FEZ, HH22, ZNF312B |
Species | Human |
Gene Type | protein-coding |
Description | FEZ family zinc finger 1 |
Other Description | fez family zinc finger protein 1|zinc finger protein 312B |
Swissprots | B7ZM98 A0PJY2 A0PJY3 A4D0W3 B4DUP9 |
Accessions | A0PJY2 EAL24342 EAW83568 AK300742 BAG62411 AY726588 BC127714 AAI27715 BC127715 AAI27716 BC136684 AAI36685 BC144367 AAI44368 CB104829 DC386457 HY206093 XM_005250337 XP_005250394 XM_011516200 XP_011514502 XM_011516201 XP_011514503 XM_011516202 XP_011514504 NM_001024613 NP_001019784 NM_001160264 NP_001153736 |
Function | Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19318583}. |
Tissue Specificity | Expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2- to 20-fold increase is found in over 50% of gastric cancer tissues. {ECO:0000269|PubMed:19318583}. |
FEZF1 CRISPR/Cas9 KO Plasmid (h) - sc-407443 from Santa Cruz Biotechnology
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FEZF1 HDR Plasmid (h) - sc-407443-HDR from Santa Cruz Biotechnology
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FEZF1 Double Nickase Plasmid (h) - sc-407443-NIC from Santa Cruz Biotechnology
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FEZF1 Double Nickase Plasmid (h2) - sc-407443-NIC-2 from Santa Cruz Biotechnology
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FEZF1 CRISPR Activation Plasmid (h) - sc-407443-ACT from Santa Cruz Biotechnology
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FEZF1 CRISPR Activation Plasmid (h2) - sc-407443-ACT-2 from Santa Cruz Biotechnology
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FEZF1 Lentiviral Activation Particles (h) - sc-407443-LAC from Santa Cruz Biotechnology
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FEZF1 Lentiviral Activation Particles (h2) - sc-407443-LAC-2 from Santa Cruz Biotechnology
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FEZF1 siRNA (h) - sc-89824 from Santa Cruz Biotechnology
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FEZF1 shRNA Plasmid (h) - sc-89824-SH from Santa Cruz Biotechnology
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FEZF1 shRNA (h) Lentiviral Particles - sc-89824-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8633 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8633 from Sigma-Aldrich
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FEZF1 siRNA (Human) - CRJ7889 from Cohesion Biosciences
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FEZF1 - MBS8229482 from MyBioSource
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shRNA set against Human FEZF1 (NM_001024613.2) - SHH294205 from Creative biogene
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Human FEZF1 siRNA - orb278390 from Biorbyt
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FEZF1 shRNA Plasmid (Human) - CHJ7889 from Cohesion Biosciences
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FEZF1 miRNA 3'UTR clone - MiUTR4H-TG11212 from Creative biogene
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