GALE

Gene Symbol	GALE
Entrez Gene	2582
Alt Symbol	SDR1E1
Species	Human
Gene Type	protein-coding
Description	UDP-galactose-4-epimerase
Other Description	UDP galactose-4'-epimerase|UDP-GalNAc 4-epimerase|UDP-GlcNAc 4-epimerase|UDP-N-acetylgalactosamine 4-epimerase|UDP-N-acetylglucosamine 4-epimerase|UDP-galactose 4-epimerase|UDP-glucose 4-epimerase|galactose-4-epimerase, UDP-|galactowaldenase|short chain dehydrogenase/reductase family 1E, member 1
Swissprots	Q86W41 Q14376 Q9UJB4 A0A024RAH5 Q9BVE3 Q38G75 B3KQ39
Accessions	AAC39645 ABB04109 CBX87741 EAW95083 EAW95084 EAW95085 EAW95086 EAW95087 EAW95088 EAW95089 EAW95090 EAW95091 EAW95092 EAW95093 Q14376 AK057302 BAG51901 AK096127 AK307354 AK314397 BAG37021 AL530475 BC001273 AAH01273 BC050685 AAH50685 BC056880 BI835132 BQ437612 DA043957 DQ233668 ABB04110 DQ891753 ABM82679 DQ894934 ABM85860 L41668 AAB86498 NM_000403 NP_000394 NM_001008216 NP_001008217 NM_001127621 NP_001121093
Function	Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6- phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP- GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. {ECO:0000269|PubMed:22654673, ECO:0000303|PubMed:23732289}.
Top Pathways	Amino sugar and nucleotide sugar metabolism, Galactose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GALE full length protein - ab96767 from Abcam Category Protein Source E. coli Species Human

GALE / UDP-Glucose 4-Epimerase Antibody Blocking Peptide - LS-E19576 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GALE / UDP-Glucose 4-Epimerase Antibody Blocking Peptide - LS-E19577 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GALE / UDP-Glucose 4-Epimerase Antibody Blocking Peptide - LS-E8535 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GALE Recombinant Protein - H00002582-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human GALE Protein - NBP1-45279 from Novus Biologicals Category Protein Prices $269.00, $629.00 Sizes 100 µg, 500 µg Source E. coli Species Human

GALE-Antibody-Center-Blocking-Peptide - BP6902c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GALE Protein (OPPA02391) - OPPA02391 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human GALE protein - orb90103 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E.coli Species Human

Human GALE protein (His Tag) - orb138900 from Biorbyt Category Protein Prices $298.00, $612.00 Sizes 20 μg, 100 μg Source E. coli Species Human

GALE Blocking Peptide - 33R-1135 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GALE Blocking Peptide - 33R-7297 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GALE protein (His tag) - 80R-1377 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

GALE (1-348, His-tag) - AR09551PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

GALE (1-348, His-tag) - AR09551PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

GALE - H00002582-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

GALE - H00002582-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

UDP-Galactose-4-Epimerase, Human Recombinant - 228-12554-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human UDP-Galactose-4-Epimerase - 228-12554-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human UDP-Galactose-4-Epimerase - 228-12554-3 from RayBiotech Category Protein Prices $2,400.00 Sizes 3 µg Source Escherichia Coli. Species Human

GALE, 1-348aa, Human, His tag, E.coli - 01-1871 from ARP American Research Products Category Protein Prices $159.00, $339.00, $749.00 Sizes 20 µg, 100 µg, 500 µg Species Human

UDP-Glucose 4-Epimerase, GALE, Human, Recombinant - 19-C263 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

UDP glucose 4 epimerase Recombinant Protein - 96-339 from ProSci Category Protein Prices $300.00 Sizes 100 µg Source E. coli Species Human

GALE fusion protein - Ag6571 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

GALE fusion protein - Ag5756 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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