| Gene Symbol |
RGS22
|
| Entrez Gene |
26166
|
| Alt Symbol |
CT145, PRTD-NY2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulator of G-protein signaling 22
|
| Other Description |
-
|
| Swissprots |
Q9BYZ4 Q569L2 A8K944 Q8NE09 Q9UFN6 Q86Y71
|
| Accessions |
EAW91794 EAW91795 EAW91796 EAW91797 Q8NE09 AK097399 BAG53465 AK292559 BAF85248 AK302475 BAG63763 AK309194 AL117544 CAB55986 AY009106 AAG49397 BC036665 AAH36665 BC047060 AAH47060 BC050053 BC092411 AAH92411 BM684810 XM_005250856 XP_005250913 XM_005250857 XP_005250914 XM_005250858 XP_005250915 XM_005250860 XP_005250917 XM_006716540 XP_006716603 XM_011516957 XP_011515259 XM_011516958 XP_011515260 XM_011516959 XP_011515261 XR_928317 NM_001286692 NP_001273621 NM_001286693 NP_001273622 NM_015668 NP_056483
|
| Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18703424}. Nucleus {ECO:0000269|PubMed:18703424}. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus.
|
| Tissue Specificity |
Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level). {ECO:0000269|PubMed:18703424}.
|