Gene Symbol | RGS22 |
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Entrez Gene | 26166 |
Alt Symbol | CT145, PRTD-NY2 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 22 |
Other Description | - |
Swissprots | Q9BYZ4 Q569L2 A8K944 Q8NE09 Q9UFN6 Q86Y71 |
Accessions | EAW91794 EAW91795 EAW91796 EAW91797 Q8NE09 AK097399 BAG53465 AK292559 BAF85248 AK302475 BAG63763 AK309194 AL117544 CAB55986 AY009106 AAG49397 BC036665 AAH36665 BC047060 AAH47060 BC050053 BC092411 AAH92411 BM684810 XM_005250856 XP_005250913 XM_005250857 XP_005250914 XM_005250858 XP_005250915 XM_005250860 XP_005250917 XM_006716540 XP_006716603 XM_011516957 XP_011515259 XM_011516958 XP_011515260 XM_011516959 XP_011515261 XR_928317 NM_001286692 NP_001273621 NM_001286693 NP_001273622 NM_015668 NP_056483 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18703424}. Nucleus {ECO:0000269|PubMed:18703424}. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus. |
Tissue Specificity | Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level). {ECO:0000269|PubMed:18703424}. |
RGS22 CRISPR/Cas9 KO Plasmid (h) - sc-411891 from Santa Cruz Biotechnology
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RGS22 HDR Plasmid (h) - sc-411891-HDR from Santa Cruz Biotechnology
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RGS22 Double Nickase Plasmid (h) - sc-411891-NIC from Santa Cruz Biotechnology
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RGS22 Double Nickase Plasmid (h2) - sc-411891-NIC-2 from Santa Cruz Biotechnology
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RGS22 CRISPR Activation Plasmid (h) - sc-411891-ACT from Santa Cruz Biotechnology
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RGS22 CRISPR Activation Plasmid (h2) - sc-411891-ACT-2 from Santa Cruz Biotechnology
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RGS22 Lentiviral Activation Particles (h) - sc-411891-LAC from Santa Cruz Biotechnology
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RGS22 Lentiviral Activation Particles (h2) - sc-411891-LAC-2 from Santa Cruz Biotechnology
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RGS22 siRNA (h) - sc-77832 from Santa Cruz Biotechnology
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RGS22 shRNA Plasmid (h) - sc-77832-SH from Santa Cruz Biotechnology
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RGS22 shRNA (h) Lentiviral Particles - sc-77832-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN18227 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18227 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01101 from Sigma-Aldrich
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RGS22 siRNA (Human) - CRH8745 from Cohesion Biosciences
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RGS22 - MBS8213446 from MyBioSource
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shRNA set against Human RGS22 (NM_015668.3) - SHH394956 from Creative biogene
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shRNA set against Human RGS22(NM_015668.3) - SHR179268 from Creative biogene
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RGS22 shRNA Plasmid (Human) - CHH8745 from Cohesion Biosciences
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RGS22 miRNA 3'UTR clone - MiUTR1H-08787 from Creative biogene
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