| Gene Symbol |
TRAT1
|
| Entrez Gene |
50852
|
| Alt Symbol |
HSPC062, TCRIM, TRIM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
T cell receptor associated transmembrane adaptor 1
|
| Other Description |
T cell receptor interacting molecule|T-cell receptor interacting molecule|T-cell receptor-associated transmembrane adapter 1|T-cell receptor-interacting molecule|pp29/30
|
| Swissprots |
Q9NZX5 Q6PIZ9
|
| Accessions |
EAW79717 EAW79718 Q6PIZ9 AF161547 AAF29034 AJ224878 CAA12178 AJ240085 CAB72134 AK291991 BAF84680 BC025713 AAH25713 BX111605 BX329167 BX415345 DQ892053 ABM82979 DQ895247 ABM86173 NM_016388 NP_057472
|
| Function |
Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. {ECO:0000269|PubMed:11390434}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:9687533}; Single-pass type III membrane protein {ECO:0000269|PubMed:9687533}.
|
| Tissue Specificity |
Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level). {ECO:0000269|PubMed:16160011, ECO:0000269|PubMed:9687533}.
|
![Western Blot: TRIM Overexpression Lysate (Adult Normal) [NBP2-07044] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TRIM.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8350_TRIM%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07044-img0001.jpg)