Gene Symbol | TRAT1 |
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Entrez Gene | 50852 |
Alt Symbol | HSPC062, TCRIM, TRIM |
Species | Human |
Gene Type | protein-coding |
Description | T cell receptor associated transmembrane adaptor 1 |
Other Description | T cell receptor interacting molecule|T-cell receptor interacting molecule|T-cell receptor-associated transmembrane adapter 1|T-cell receptor-interacting molecule|pp29/30 |
Swissprots | Q9NZX5 Q6PIZ9 |
Accessions | EAW79717 EAW79718 Q6PIZ9 AF161547 AAF29034 AJ224878 CAA12178 AJ240085 CAB72134 AK291991 BAF84680 BC025713 AAH25713 BX111605 BX329167 BX415345 DQ892053 ABM82979 DQ895247 ABM86173 NM_016388 NP_057472 |
Function | Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. {ECO:0000269|PubMed:11390434}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:9687533}; Single-pass type III membrane protein {ECO:0000269|PubMed:9687533}. |
Tissue Specificity | Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level). {ECO:0000269|PubMed:16160011, ECO:0000269|PubMed:9687533}. |
TRIM CRISPR/Cas9 KO Plasmid (h) - sc-418426 from Santa Cruz Biotechnology
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TRIM HDR Plasmid (h) - sc-418426-HDR from Santa Cruz Biotechnology
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TRIM Double Nickase Plasmid (h) - sc-418426-NIC from Santa Cruz Biotechnology
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TRIM Double Nickase Plasmid (h2) - sc-418426-NIC-2 from Santa Cruz Biotechnology
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TRIM CRISPR Activation Plasmid (h) - sc-418426-ACT from Santa Cruz Biotechnology
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TRIM CRISPR Activation Plasmid (h2) - sc-418426-ACT-2 from Santa Cruz Biotechnology
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TRIM Lentiviral Activation Particles (h) - sc-418426-LAC from Santa Cruz Biotechnology
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TRIM Lentiviral Activation Particles (h2) - sc-418426-LAC-2 from Santa Cruz Biotechnology
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TRIM siRNA (h) - sc-106637 from Santa Cruz Biotechnology
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TRIM shRNA Plasmid (h) - sc-106637-SH from Santa Cruz Biotechnology
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TRIM shRNA (h) Lentiviral Particles - sc-106637-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU003921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21933 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21933 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08222 from Sigma-Aldrich
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TRAT1 siRNA (Human) - CRH9424 from Cohesion Biosciences
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TRAT1 - MBS8205207 from MyBioSource
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shRNA set against Human TRAT1 (NM_016388.2) - SHH434040 from Creative biogene
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shRNA set against Human TRAT1(NM_016388.2) - SHL092088 from Creative biogene
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Human TRAT1 siRNA - orb269926 from Biorbyt
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TRAT1 shRNA Plasmid (Human) - CHH9424 from Cohesion Biosciences
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TRAT1 miRNA 3'UTR clone - MiUTR1H-10704 from Creative biogene
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