Gene Symbol | CKB |
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Entrez Gene | 1152 |
Alt Symbol | B-CK, BCK, CKBB, HEL-211, HEL-S-29 |
Species | Human |
Gene Type | protein-coding |
Description | creatine kinase, brain |
Other Description | creatine kinase B chain|creatine kinase B-type|creatine kinase-B|epididymis luminal protein 211|epididymis secretory protein Li 29 |
Swissprots | B2R5R4 A8K236 Q6FG40 Q2LE07 Q9UC66 P12277 |
Accessions | AAA52024 AAC31758 ABC67465 CAA33389 EAW81820 EAW81821 EAW81822 P12277 AK290101 BAF82790 AK298198 BAG60468 AK312282 BAG35211 BC001190 AAH01190 BC004914 AAH04914 BC008323 AAH08323 BC010002 AAH10002 BC019259 AAH19259 BC019281 AAH19281 BG720434 BM684665 BP213119 CR542268 CAG47064 EU794629 ACJ13683 FJ224337 ACI46029 JF432538 ADZ15755 L47647 AAA76852 M16364 AAA76850 M16451 AAA76851 NM_001823 NP_001814 |
Function | Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. |
Subcellular Location | Cytoplasm. |
Top Pathways | Arginine and proline metabolism |
creatine kinase-B CRISPR/Cas9 KO Plasmid (h) - sc-401868 from Santa Cruz Biotechnology
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creatine kinase-B HDR Plasmid (h) - sc-401868-HDR from Santa Cruz Biotechnology
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creatine kinase-B Double Nickase Plasmid (h) - sc-401868-NIC from Santa Cruz Biotechnology
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creatine kinase-B Double Nickase Plasmid (h2) - sc-401868-NIC-2 from Santa Cruz Biotechnology
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creatine kinase-B CRISPR Activation Plasmid (h) - sc-401868-ACT from Santa Cruz Biotechnology
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creatine kinase-B CRISPR Activation Plasmid (h2) - sc-401868-ACT-2 from Santa Cruz Biotechnology
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creatine kinase-B Lentiviral Activation Particles (h) - sc-401868-LAC from Santa Cruz Biotechnology
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creatine kinase-B Lentiviral Activation Particles (h2) - sc-401868-LAC-2 from Santa Cruz Biotechnology
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creatine kinase-B siRNA (h) - sc-35107 from Santa Cruz Biotechnology
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creatine kinase-B shRNA Plasmid (h) - sc-35107-SH from Santa Cruz Biotechnology
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creatine kinase-B shRNA (h) Lentiviral Particles - sc-35107-V from Santa Cruz Biotechnology
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Creatine Kinase B RNAi - H00001152-R02 from Novus Biologicals
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MISSION® esiRNA - EHU153971 from Sigma-Aldrich
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MISSION® siRNA - SIHK0428 from Sigma-Aldrich
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MISSION® siRNA - SIHK0430 from Sigma-Aldrich
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MISSION® siRNA - SIHK0429 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6152 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6152 from Sigma-Aldrich
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CKB siRNA (Human) - CRH0826 from Cohesion Biosciences
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CKB - MBS8219278 from MyBioSource
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creatine kinase-B CRISPR/Cas9 KO Plasmid (h2) - sc-401868-KO-2 from Santa Cruz Biotechnology
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creatine kinase-B HDR Plasmid (h2) - sc-401868-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CKB (NM_001823.4) - SHH264353 from Creative biogene
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Human CKB siRNA - orb261328 from Biorbyt
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CKB shRNA Plasmid (Human) - CHH0826 from Cohesion Biosciences
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