Gene Symbol | NODAL |
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Entrez Gene | 4838 |
Alt Symbol | HTX5 |
Species | Human |
Gene Type | protein-coding |
Description | nodal growth differentiation factor |
Other Description | nodal homolog |
Swissprots | Q96S42 Q8N4V3 Q2M3A5 |
Accessions | BAB62524 EAW54403 Q96S42 BC033585 AAH33585 BC039861 BC104976 AAI04977 BC112025 AAI12026 NM_018055 NP_060525 |
Function | Essential for mesoderm formation and axial patterning during embryonic development. {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Nodal CRISPR/Cas9 KO Plasmid (h) - sc-401439 from Santa Cruz Biotechnology
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Nodal HDR Plasmid (h) - sc-401439-HDR from Santa Cruz Biotechnology
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Nodal Double Nickase Plasmid (h) - sc-401439-NIC from Santa Cruz Biotechnology
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Nodal Double Nickase Plasmid (h2) - sc-401439-NIC-2 from Santa Cruz Biotechnology
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Nodal CRISPR Activation Plasmid (h) - sc-401439-ACT from Santa Cruz Biotechnology
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Nodal CRISPR Activation Plasmid (h2) - sc-401439-ACT-2 from Santa Cruz Biotechnology
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Nodal Lentiviral Activation Particles (h) - sc-401439-LAC from Santa Cruz Biotechnology
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Nodal Lentiviral Activation Particles (h2) - sc-401439-LAC-2 from Santa Cruz Biotechnology
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Nodal siRNA (h) - sc-45478 from Santa Cruz Biotechnology
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Nodal shRNA Plasmid (h) - sc-45478-SH from Santa Cruz Biotechnology
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Nodal shRNA (h) Lentiviral Particles - sc-45478-V from Santa Cruz Biotechnology
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Nodal RNAi - H00004838-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN15394 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15394 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05527 from Sigma-Aldrich
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NODAL siRNA (Human) - CRH3214 from Cohesion Biosciences
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Nodal CRISPR/Cas9 KO Plasmid (h2) - sc-401439-KO-2 from Santa Cruz Biotechnology
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Nodal HDR Plasmid (h2) - sc-401439-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human NODAL (NM_018055.4) - SHH353464 from Creative biogene
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Human NODAL siRNA - orb263716 from Biorbyt
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NODAL shRNA Plasmid (Human) - CHH3214 from Cohesion Biosciences
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NODAL miRNA 3'UTR clone - MiUTR3H-04006 from Creative biogene
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