ARF1

Gene Symbol	ARF1
Entrez Gene	375
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ADP-ribosylation factor 1
Other Description	-
Swissprots	P84077
Accessions	AAA35511 EAW69831 EAW69832 EAW69833 EAW69834 EAW69835 EAW69836 P84077 AF052179 AAC28623 AF055002 AAC09356 AF493881 AAM12595 AK000620 AK057838 AK057875 AK130737 AK293553 BAG57030 AK296020 BAG58790 AK297792 BAG60132 AM393261 CAL38139 AM393462 CAL38339 AM393595 CAL38472 AM393712 CAL38588 BC009247 AAH09247 BC010415 BC010429 AAH10429 BC011358 AAH11358 BF337061 BG421840 BM353046 BM844480 BQ935470 BQ949763 BT007393 AAP36057 M36340 AAA35552 M84326 AAA35512 NM_001024226 NP_001019397 NM_001024227 NP_001019398 NM_001024228 NP_001019399 NM_001658 NP_001649
Function	GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Subcellular Location	Golgi apparatus {ECO:0000269|PubMed:17555535}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:17555535}. Cell junction, synapse, synaptosome {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}.
Top Pathways	Vibrio cholerae infection, Endocytosis, Legionellosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ARF1 (deletion E17) full length protein - ab176619 from Abcam Category Protein Prices $378.00 Sizes 10 µg Source E. coli Species Human

Human ARF1 (deletion E17, mutated Q71 L) full length protein - ab176675 from Abcam Category Protein Prices $378.00 Sizes 10 µg Source E. coli Species Human

Human ARF1 full length protein - ab123538 from Abcam Category Protein Prices $188.00 Sizes 5 µg Source E. coli Species Human

ARF1 Antibody Blocking Peptide - LS-E8018 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARF1 Antibody Blocking Peptide - LS-E17433 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARF1 Antibody Blocking Peptide - LS-E17434 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARF1/2/3/4 Antibody Blocking Peptide - LS-E26231 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARF1 Partial Recombinant Protein - H00000375-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ARF1 Protein - H00000375-P01 from Novus Biologicals Category Protein Prices $319.00, $529.00 Sizes 2 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ARF1 Protein - NBP1-45297 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

ARF1-Antibody-Center-Blocking-peptide - BP5871c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARF1, 2, 3, 4 blocking peptide - GTX89179-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

ARF1 Protein (OPPA02255) - OPPA02255 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human ADP-ribosylation factor 1 (His Tag) protein - orb179562 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human ADP-Ribosylation Factor 1 protein - orb80924 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

ARF1 Blocking Peptide - 33R-4444 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ARF1 Blocking Peptide - 33R-6371 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ARF1 protein (His tag) - 80R-1406 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

ARF1 Peptide - AC21-1062-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ARF1 (1-181, His-tag) - AR09581PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ARF1 (1-181, His-tag) - AR09581PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ADP-ribosylation factor 1 (ARF1) - H00000375-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ADP-ribosylation factor 1 (ARF1) - H00000375-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ADP-ribosylation factor 1 (ARF1) - H00000375-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ADP-ribosylation factor 1 (ARF1) - H00000375-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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