Gene Symbol |
CST11
|
Entrez Gene |
140880
|
Alt Symbol |
CST8L, CTES2, SC13, dJ322G13.6
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cystatin 11
|
Other Description |
SC13delta|cystatin-11|cystatin-related epididymal-specific protein
|
Swissprots |
Q8WXU6 Q0VAF2 Q9H113 Q0VAF3 Q9H112 Q8WXU5
|
Accessions |
EAX10146 EAX10147 Q9H112 AF335480 AAL71991 AF335481 AAL71992 BC121079 AAI21080 BC121080 AAI21081 NM_080830 NP_543020 NM_130794 NP_570612
|
Function |
Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. {ECO:0000269|PubMed:12072414}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:12072414}. Cytoplasm {ECO:0000269|PubMed:12072414}. Note=Nuclear and cytoplasmic in the epididymis. Localized to the postacrosomal and tail regions of sperm. Probably localized to the outer surface of sperm.
|
Tissue Specificity |
Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level). {ECO:0000269|PubMed:12072414}.
|