Gene Symbol | CST11 |
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Entrez Gene | 140880 |
Alt Symbol | CST8L, CTES2, SC13, dJ322G13.6 |
Species | Human |
Gene Type | protein-coding |
Description | cystatin 11 |
Other Description | SC13delta|cystatin-11|cystatin-related epididymal-specific protein |
Swissprots | Q8WXU6 Q0VAF2 Q9H113 Q0VAF3 Q9H112 Q8WXU5 |
Accessions | EAX10146 EAX10147 Q9H112 AF335480 AAL71991 AF335481 AAL71992 BC121079 AAI21080 BC121080 AAI21081 NM_080830 NP_543020 NM_130794 NP_570612 |
Function | Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. {ECO:0000269|PubMed:12072414}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12072414}. Cytoplasm {ECO:0000269|PubMed:12072414}. Note=Nuclear and cytoplasmic in the epididymis. Localized to the postacrosomal and tail regions of sperm. Probably localized to the outer surface of sperm. |
Tissue Specificity | Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level). {ECO:0000269|PubMed:12072414}. |
cystatin 11 CRISPR/Cas9 KO Plasmid (h) - sc-414503 from Santa Cruz Biotechnology
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cystatin 11 HDR Plasmid (h) - sc-414503-HDR from Santa Cruz Biotechnology
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cystatin 11 Double Nickase Plasmid (h) - sc-414503-NIC from Santa Cruz Biotechnology
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cystatin 11 Double Nickase Plasmid (h2) - sc-414503-NIC-2 from Santa Cruz Biotechnology
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cystatin 11 CRISPR Activation Plasmid (h) - sc-414503-ACT from Santa Cruz Biotechnology
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cystatin 11 CRISPR Activation Plasmid (h2) - sc-414503-ACT-2 from Santa Cruz Biotechnology
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cystatin 11 Lentiviral Activation Particles (h) - sc-414503-LAC from Santa Cruz Biotechnology
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cystatin 11 Lentiviral Activation Particles (h2) - sc-414503-LAC-2 from Santa Cruz Biotechnology
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cystatin 11 siRNA (h) - sc-77080 from Santa Cruz Biotechnology
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cystatin 11 shRNA Plasmid (h) - sc-77080-SH from Santa Cruz Biotechnology
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cystatin 11 shRNA (h) Lentiviral Particles - sc-77080-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN6670 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6670 from Sigma-Aldrich
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CST11 siRNA (Human) - CRJ5339 from Cohesion Biosciences
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CST11 - MBS8239318 from MyBioSource
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shRNA set against Human Cst11 (NM_080830.2) - SHH270709 from Creative biogene
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shRNA set against Human CST11(NM_080830.2) - SHG204659 from Creative biogene
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shRNA set against Human CST11(NM_130794.1) - SHG204713 from Creative biogene
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Human CST11 siRNA - orb275840 from Biorbyt
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CST11 shRNA Plasmid (Human) - CHJ5339 from Cohesion Biosciences
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CST11 miRNA 3'UTR clone - MiUTR1H-02490 from Creative biogene
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CST11 miRNA 3'UTR clone - MiUTR1H-02491 from Creative biogene
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