| Gene Symbol |
SLC4A3
|
| Entrez Gene |
6508
|
| Alt Symbol |
AE3, SLC2C
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 4 (anion exchanger), member 3
|
| Other Description |
AE 3|Anion exchanger 3, neuronal|CAE3/BAE3|anion exchange protein 3|anion exchanger 3 cardiac isoform|cardiac/brain band 3-like protein|neuronal band 3-like protein|solute carrier family 4 member 3
|
| Swissprots |
A8K1Q9 A6H8L2 B7ZVX6 P48751 Q6YIQ9 B9EGD1
|
| Accessions |
EAW70777 EAW70778 P48751 AK226122 AK289974 BAF82663 AK299109 BAG61165 AK299595 BAG61527 AK309025 AK314083 AY142112 AAN34939 BC136384 AAI36385 BC146656 AAI46657 BC171760 AAI71760 L27213 AAB05850 U05596 AAA50748 U05597 AAA50749 X70797 CAA50067 X87211 CAA60670 XM_005246789 XP_005246846 XM_005246790 XP_005246847 XM_011511665 XP_011509967 XM_011511666 XP_011509968 XM_011511667 XP_011509969 NM_005070 NP_005061 NM_201574 NP_963868 NR_048551
|
| Function |
Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-).
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Both BAE3 and CAE3 are expressed in failing ventricle.
|