Gene Symbol | SLC4A3 |
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Entrez Gene | 6508 |
Alt Symbol | AE3, SLC2C |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 4 (anion exchanger), member 3 |
Other Description | AE 3|Anion exchanger 3, neuronal|CAE3/BAE3|anion exchange protein 3|anion exchanger 3 cardiac isoform|cardiac/brain band 3-like protein|neuronal band 3-like protein|solute carrier family 4 member 3 |
Swissprots | A8K1Q9 A6H8L2 B7ZVX6 P48751 Q6YIQ9 B9EGD1 |
Accessions | EAW70777 EAW70778 P48751 AK226122 AK289974 BAF82663 AK299109 BAG61165 AK299595 BAG61527 AK309025 AK314083 AY142112 AAN34939 BC136384 AAI36385 BC146656 AAI46657 BC171760 AAI71760 L27213 AAB05850 U05596 AAA50748 U05597 AAA50749 X70797 CAA50067 X87211 CAA60670 XM_005246789 XP_005246846 XM_005246790 XP_005246847 XM_011511665 XP_011509967 XM_011511666 XP_011509968 XM_011511667 XP_011509969 NM_005070 NP_005061 NM_201574 NP_963868 NR_048551 |
Function | Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-). |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Both BAE3 and CAE3 are expressed in failing ventricle. |
AE3 CRISPR/Cas9 KO Plasmid (h) - sc-411006 from Santa Cruz Biotechnology
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AE3 HDR Plasmid (h) - sc-411006-HDR from Santa Cruz Biotechnology
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AE3 Double Nickase Plasmid (h) - sc-411006-NIC from Santa Cruz Biotechnology
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AE3 Double Nickase Plasmid (h2) - sc-411006-NIC-2 from Santa Cruz Biotechnology
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AE3 CRISPR Activation Plasmid (h) - sc-411006-ACT from Santa Cruz Biotechnology
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AE3 CRISPR Activation Plasmid (h2) - sc-411006-ACT-2 from Santa Cruz Biotechnology
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AE3 Lentiviral Activation Particles (h) - sc-411006-LAC from Santa Cruz Biotechnology
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AE3 Lentiviral Activation Particles (h2) - sc-411006-LAC-2 from Santa Cruz Biotechnology
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AE3 siRNA (h) - sc-72460 from Santa Cruz Biotechnology
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AE3 shRNA Plasmid (h) - sc-72460-SH from Santa Cruz Biotechnology
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AE3 shRNA (h) Lentiviral Particles - sc-72460-V from Santa Cruz Biotechnology
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SLC4A3 RNAi - H00006508-R02 from Novus Biologicals
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SLC4A3 RNAi - H00006508-R01 from Novus Biologicals
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MISSION® esiRNA - EHU157691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19653 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19653 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01129 from Sigma-Aldrich
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SLC4A3 siRNA (Human) - CRH4403 from Cohesion Biosciences
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SLC4A3 - MBS8203204 from MyBioSource
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shRNA set against Human SLC4A3 (NM_005070.3) - SHH411560 from Creative biogene
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shRNA set against Human SLC4A3(NM_201574.2) - SHL009854 from Creative biogene
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shRNA set against Human SLC4A3(NM_005070.3) - SHL009872 from Creative biogene
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Human SLC4A3 siRNA - orb264905 from Biorbyt
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SLC4A3 shRNA Plasmid (Human) - CHH4403 from Cohesion Biosciences
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SLC4A3 miRNA 3'UTR clone - MiUTR1H-09579 from Creative biogene
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