| Gene Symbol |
VPS37C
|
| Entrez Gene |
55048
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuolar protein sorting 37 homolog C (S. cerevisiae)
|
| Other Description |
ESCRT-I complex subunit VPS37C|hVps37C|vacuolar protein sorting 37C|vacuolar protein sorting-associated protein 37C
|
| Swissprots |
Q8N3K4 A5D8V6
|
| Accessions |
A5D8V6 EAW73925 EAW73926 EAW73927 AK000854 BAA91399 AK097326 AK302384 BAG63701 AL834261 CAD38936 BC005805 BC062604 BC141827 AAI41828 BC142702 AAI42703 BM450171 CR457250 CAG33531 XM_005274077 XP_005274134 NM_017966 NP_060436
|
| Function |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:15509564}.
|
| Subcellular Location |
Late endosome membrane {ECO:0000305|PubMed:15509564}; Peripheral membrane protein {ECO:0000305|PubMed:15509564}. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1.
|
| Top Pathways |
Endocytosis
|