Gene Symbol | VPS37C |
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Entrez Gene | 55048 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
Other Description | ESCRT-I complex subunit VPS37C|hVps37C|vacuolar protein sorting 37C|vacuolar protein sorting-associated protein 37C |
Swissprots | Q8N3K4 A5D8V6 |
Accessions | A5D8V6 EAW73925 EAW73926 EAW73927 AK000854 BAA91399 AK097326 AK302384 BAG63701 AL834261 CAD38936 BC005805 BC062604 BC141827 AAI41828 BC142702 AAI42703 BM450171 CR457250 CAG33531 XM_005274077 XP_005274134 NM_017966 NP_060436 |
Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:15509564}. |
Subcellular Location | Late endosome membrane {ECO:0000305|PubMed:15509564}; Peripheral membrane protein {ECO:0000305|PubMed:15509564}. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1. |
Top Pathways | Endocytosis |
VPS37C CRISPR/Cas9 KO Plasmid (h) - sc-412426 from Santa Cruz Biotechnology
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VPS37C HDR Plasmid (h) - sc-412426-HDR from Santa Cruz Biotechnology
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VPS37C Double Nickase Plasmid (h) - sc-412426-NIC from Santa Cruz Biotechnology
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VPS37C Double Nickase Plasmid (h2) - sc-412426-NIC-2 from Santa Cruz Biotechnology
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VPS37C CRISPR Activation Plasmid (h) - sc-412426-ACT from Santa Cruz Biotechnology
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VPS37C CRISPR Activation Plasmid (h2) - sc-412426-ACT-2 from Santa Cruz Biotechnology
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VPS37C Lentiviral Activation Particles (h) - sc-412426-LAC from Santa Cruz Biotechnology
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VPS37C Lentiviral Activation Particles (h2) - sc-412426-LAC-2 from Santa Cruz Biotechnology
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VPS37C siRNA (h) - sc-97065 from Santa Cruz Biotechnology
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VPS37C shRNA Plasmid (h) - sc-97065-SH from Santa Cruz Biotechnology
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VPS37C shRNA (h) Lentiviral Particles - sc-97065-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22723 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22723 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12728 from Sigma-Aldrich
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VPS37C siRNA (Human) - CRJ0430 from Cohesion Biosciences
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VPS37C - MBS8220906 from MyBioSource
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shRNA set against Human VPS37C (NM_017966.4) - SHH445000 from Creative biogene
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shRNA set against Human VPS37C(NM_017966.4) - SHL127866 from Creative biogene
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Human VPS37C siRNA - orb270931 from Biorbyt
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VPS37C shRNA Plasmid (Human) - CHJ0430 from Cohesion Biosciences
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VPS37C miRNA 3'UTR clone - MiUTR1H-11154 from Creative biogene
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