Gene Symbol |
FNTB
|
Entrez Gene |
2342
|
Alt Symbol |
FPTB
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
farnesyltransferase, CAAX box, beta
|
Other Description |
CAAX farnesyltransferase subunit beta|FTase-beta|protein farnesyltransferase subunit beta|ras proteins prenyltransferase subunit beta
|
Swissprots |
B2RDX6 P49356 B4E1A0
|
Accessions |
AAB26815 EAW80897 P49356 AK093298 BAG52684 AK225917 AK295972 BAG58748 AK315714 BAG38073 AU122768 BC013574 BC020232 AAH20232 BM990350 BX248269 CAD62597 DQ892128 ABM83054 DQ895321 ABM86247 L00635 AAA35854 L10414 AAA86286 NM_002028 NP_002019
|
Function |
Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X. {ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:16893176, ECO:0000269|PubMed:19246009, ECO:0000269|PubMed:8494894}.
|
Top Pathways |
Terpenoid backbone biosynthesis
|