Gene Symbol | FNTB |
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Entrez Gene | 2342 |
Alt Symbol | FPTB |
Species | Human |
Gene Type | protein-coding |
Description | farnesyltransferase, CAAX box, beta |
Other Description | CAAX farnesyltransferase subunit beta|FTase-beta|protein farnesyltransferase subunit beta|ras proteins prenyltransferase subunit beta |
Swissprots | B2RDX6 P49356 B4E1A0 |
Accessions | AAB26815 EAW80897 P49356 AK093298 BAG52684 AK225917 AK295972 BAG58748 AK315714 BAG38073 AU122768 BC013574 BC020232 AAH20232 BM990350 BX248269 CAD62597 DQ892128 ABM83054 DQ895321 ABM86247 L00635 AAA35854 L10414 AAA86286 NM_002028 NP_002019 |
Function | Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X. {ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:16893176, ECO:0000269|PubMed:19246009, ECO:0000269|PubMed:8494894}. |
Top Pathways | Terpenoid backbone biosynthesis |
FTβ siRNA (h) - sc-35417 from Santa Cruz Biotechnology
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FTβ shRNA Plasmid (h) - sc-35417-SH from Santa Cruz Biotechnology
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FTβ shRNA (h) Lentiviral Particles - sc-35417-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8864 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8864 from Sigma-Aldrich
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FNTB siRNA (Human) - CRH1639 from Cohesion Biosciences
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shRNA set against Human FNTB (NM_002028.3) - SHH296237 from Creative biogene
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shRNA set against Human FNTB(NM_002028.3) - SHG178621 from Creative biogene
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Human FNTB siRNA - orb262141 from Biorbyt
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FNTB shRNA Plasmid (Human) - CHH1639 from Cohesion Biosciences
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FNTB miRNA 3'UTR clone - MiUTR1H-03800 from Creative biogene
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