| Gene Symbol |
TOP2B
|
| Entrez Gene |
7155
|
| Alt Symbol |
TOPIIB, top2beta
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
topoisomerase (DNA) II beta 180kDa
|
| Other Description |
DNA topoisomerase 2-beta|DNA topoisomerase II beta|DNA topoisomerase II, 180 kD|DNA topoisomerase II, beta isozyme|U937 associated antigen|antigen MLAA-44|topo II beta|topoisomerase II beta|topoisomerase IIb
|
| Swissprots |
Q9UMG8 Q9UQP8 Q02880 Q13600
|
| Accessions |
AAB54121 AAB95437 CAA09753 CAA50726 CCQ43061 EAW64357 EAW64358 EAW64359 Q02880 AB208879 BAD92116 AK296510 BAG59142 AK297171 BAG59664 AK307450 AK316492 BAH14863 BC021863 AAH21863 BC054482 BC156330 AAI56331 BC157118 AAI57119 BF514624 BM150930 M27504 AAA61210 U54831 AAB01982 X53662 CAA37706 X68060 CAA48197 Z15111 CAA78815 Z15115 CAA78821 XM_005265427 XP_005265484 XM_011534057 XP_011532359 XR_940497 NM_001068 NP_001059
|
| Function |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. {ECO:0000269|PubMed:10684600}.
|
| Subcellular Location |
Cytoplasm. Nucleus, nucleolus.
|