| Gene Symbol | USP39 |
|---|---|
| Entrez Gene | 10713 |
| Alt Symbol | 65K, CGI-21, HSPC332, SAD1, SNRNP65 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitin specific peptidase 39 |
| Other Description | SAD1 homolog|SnRNP assembly defective 1 homolog|U4/U6.U5 tri-snRNP-associated 65 kDa protein|U4/U6.U5 tri-snRNP-associated protein 2|inactive ubiquitin-specific peptidase 39|small nuclear ribonucleoprotein 65kDa (U4/U6.U5)|ubiquitin specific protease 39 |
| Swissprots | Q6NX47 Q9Y310 Q53GS9 Q9H381 Q96RK9 G5E9H0 Q9P050 D6W5L4 Q9BV89 B4DHT4 B3KM40 A8K086 |
| Accessions | EAW99490 EAW99491 EAW99492 EAW99493 EAW99494 Q53GS9 AF130096 AAG35521 AF132955 AAD27730 AF161450 AAF29010 AF353989 AAK49524 AI201523 AK001047 BAG50852 AK001772 BAG50973 AK056334 BAG51679 AK057698 AK129872 AK222852 BAD96572 AK289451 BAF82140 AK295257 BAG58246 AK302236 BAH13655 AK309485 AL117416 AL519827 BC001384 AAH01384 BC067273 AAH67273 BX462623 DA548921 DB124294 DB444135 XM_006711922 XP_006711985 XM_006711923 XP_006711986 XM_011532487 XP_011530789 XM_011532488 XP_011530790 XR_939652 XR_939653 NM_001256725 NP_001243654 NM_001256726 NP_001243655 NM_001256727 NP_001243656 NM_001256728 NP_001243657 NM_006590 NP_006581 NR_046347 |
| Function | Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs). {ECO:0000269|PubMed:11350945, ECO:0000269|PubMed:18728397}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:11350945}. |
| Top Pathways | Spliceosome |