USP39

Gene Symbol USP39
Entrez Gene 10713
Alt Symbol 65K, CGI-21, HSPC332, SAD1, SNRNP65
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 39
Other Description SAD1 homolog|SnRNP assembly defective 1 homolog|U4/U6.U5 tri-snRNP-associated 65 kDa protein|U4/U6.U5 tri-snRNP-associated protein 2|inactive ubiquitin-specific peptidase 39|small nuclear ribonucleoprotein 65kDa (U4/U6.U5)|ubiquitin specific protease 39
Swissprots Q6NX47 Q9Y310 Q53GS9 Q9H381 Q96RK9 G5E9H0 Q9P050 D6W5L4 Q9BV89 B4DHT4 B3KM40 A8K086
Accessions EAW99490 EAW99491 EAW99492 EAW99493 EAW99494 Q53GS9 AF130096 AAG35521 AF132955 AAD27730 AF161450 AAF29010 AF353989 AAK49524 AI201523 AK001047 BAG50852 AK001772 BAG50973 AK056334 BAG51679 AK057698 AK129872 AK222852 BAD96572 AK289451 BAF82140 AK295257 BAG58246 AK302236 BAH13655 AK309485 AL117416 AL519827 BC001384 AAH01384 BC067273 AAH67273 BX462623 DA548921 DB124294 DB444135 XM_006711922 XP_006711985 XM_006711923 XP_006711986 XM_011532487 XP_011530789 XM_011532488 XP_011530790 XR_939652 XR_939653 NM_001256725 NP_001243654 NM_001256726 NP_001243655 NM_001256727 NP_001243656 NM_001256728 NP_001243657 NM_006590 NP_006581 NR_046347
Function Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs). {ECO:0000269|PubMed:11350945, ECO:0000269|PubMed:18728397}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11350945}.
Top Pathways Spliceosome

USP39 (C-20) - sc-82392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP39 (C-20): sc-82392. Western blot analysis of USP39 expression in K-562 whole cell lysate.

USP39 (E-18) - sc-82393 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP39 (E-18): sc-82393. Western blot analysis of USP39 expression in Jurkat (A) and NIH/3T3 (B) nuclear extracts.

Anti-USP39 antibody - ab101902 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-USP39 antibody (ab101902) at 1 µg/mlLane 1 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 3 : HeLa (Human epithelial carcinoma cell line) Nuclear LysateLane 4 : U2OS (Human osteosarcoma cell line) Whole Cell Lysate Lane 5 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-USP39 antibody - ab168493 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-USP39 antibody (ab168493) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with USP39Lane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-USP39 antibody - ab170026 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-USP39 antibody (ab170026) at 1/500 dilutionLane 1 : Fetal liver lysateLane 2 : HepG2 cell lysate

Anti-USP39 antibody - ab104989 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-USP39 antibody (ab104989) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-USP39 antibody - ab138636 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-USP39 antibody (ab138636) at 1/100 dilution + HeLa cell lysate at 35 µg

Anti-USP39 antibody - ab56985 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56985 USP39 antibody at 1ug/ml.

Anti-USP39 antibody - ab197149 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-USP39 antibody (ab197149) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : Human fetal liver cell lysate

Anti-USP39 antibody [EPR8683] - ab131244 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8683
All lanes : Anti-USP39 antibody [EPR8683] (ab131244) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : K562 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-USP39 antibody [EPR8684] - ab131332 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8684
All lanes : Anti-USP39 antibody [EPR8684] (ab131332) at 1/10000 dilutionLane 1 : 293T cell lysateLane 2 : K562 cell lysateLane 3 : HeLa cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-USP39 Antibody (clone 3205C5a) - LS-C184800 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3205C5a

Anti-USP39 Antibody (aa237-265, AP) - LS-C207839 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (aa237-265, APC) - LS-C207840 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (aa237-265, Biotin) - LS-C207841 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (aa237-265, FITC) - LS-C207842 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (aa237-265, Azide-free, HRP) - LS-C207843 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (aa237-265, PE) - LS-C207844 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (aa236-265) - LS-C326234 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP39 Antibody (C-Terminus) - LS-C186675 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Breast Tumor. USP39 antibody dilution 1.0 ug/ml.

Anti-USP39 Antibody (aa237-265) - LS-C157334 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
USP39 Antibody western blot of HeLa cell line lysates (35 ug/lane). The USP39 antibody detected the USP39 protein (arrow).

Anti-USP39 Antibody (clone 3205C5a) - LS-C342808 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3205C5a
Western blot analysis of immunized recombinant protein, using anti-USP39 monoclonal antibody.

Anti-USP39 Antibody (C-Terminus, clone EPR8684) - LS-C154571 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8684
IHC of paraffin embedded human colon tissue using anti-USP39 antibody.

Anti-USP39 Antibody (Internal, clone EPR8683) - LS-C154496 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8683
IHC of paraffin-embedded human colonic adenocarcinoma tissue using anti-USP39 antibody.

Anti-USP39 Antibody (N-Terminus) IHC-plus™ - LS-B1114 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-USP39 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1114 concentration 5 ug/ml.
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