PDE9A

Gene Symbol	PDE9A
Entrez Gene	5152
Alt Symbol	HSPDE9A2
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 9A
Other Description	CGMP-specific 3',5'-cyclic phosphodiesterase type 9|high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A|phosphodiesterase PDE9A21
Swissprots	Q86WN4 Q5QD39 B2RBI5 Q86WP0 O75490 Q86WN6 Q86WN3 Q86WN9 Q86SJ3 Q86WN8 O75491 O76083 D3DSJ9 Q86WN5 Q86WN7 Q86SI6 D3DSJ8 Q86SF7 O95225 Q53Y40 B4DFI5
Accessions	BAA88847 BAA95552 EAX09531 EAX09532 EAX09533 EAX09534 EAX09535 EAX09536 EAX09537 EAX09538 EAX09539 EAX09540 EAX09541 EAX09542 EAX09543 EAX09544 EAX09545 EAX09546 EAX09547 EAX09548 EAX09549 O76083 AF048837 AAC39778 AF067223 AAC26723 AF067224 AAC26724 AF067225 AAC26725 AF067226 AAC26726 AI492065 AK001165 AK001307 AK074662 BAC11120 AK127770 AK294112 BAG57446 AK308753 AK314679 BAG37232 AY196299 AAO34685 AY196300 AAO34686 AY196301 AAO34687 AY196302 AAO34688 AY196303 AAO34689 AY196304 AAO34690 AY196305 AAO34691 AY196306 AAO34692 AY196307 AAO34693 AY196308 AAO34694 AY196309 AAO34695 AY196310 AAO34696 AY196311 AAO34697 AY196312 AAO34698 AY196313 AAO34699 AY196314 AAO34700 AY242121 AAO88210 AY701187 AAV84271 BC009047 AAH09047 BT007016 AAP35662 GQ129331 ACT64465 GQ129332 ACT64466 XM_011529597 XP_011527899 XM_011529598 XP_011527900 XM_011529599 XP_011527901 XM_011529600 XP_011527902 XM_011529601 XP_011527903 XR_937502 NM_001001567 NP_001001567 NM_001001568 NP_001001568 NM_001001569 NP_001001569 NM_001001570 NP_001001570 NM_001001571 NP_001001571 NM_001001572 NP_001001572 NM_001001573 NP_001001573 NM_001001574 NP_001001574 NM_001001575 NP_001001575 NM_001001576 NP_001001576 NM_001001577 NP_001001577 NM_001001578 NP_001001578 NM_001001579 NP_001001579 NM_001001580 NP_001001580 NM_001001581 NP_001001581 NM_001001582 NP_001001582 NM_001001583 NP_001001583 NM_001001584 NP_001001584 NM_001001585 NP_001001585 NM_002606 NP_002597
Function	Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. {ECO:0000269|PubMed:18757755}.
Subcellular Location	Isoform PDE9A3: Cytoplasm. Endoplasmic reticulum.
Tissue Specificity	Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate. {ECO:0000269|PubMed:12565835}.
Top Pathways	Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PDE9A full length protein - ab125666 from Abcam Category Protein Prices $302.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active human PDE9A full length protein - ab54113 from Abcam Category Protein Prices $466.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human PDE9A full length protein - ab159078 from Abcam Category Protein Source Wheat germ Species Human

Human PDE9A protein fragment - ab159079 from Abcam Category Protein Source Wheat germ Species Human

PDE9A Antibody Blocking Peptide - LS-E29228 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PDE9A Blocking Peptide - NBP1-00641PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µl

Recombinant Human PDE9A Protein - H00005152-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PDE9A Protein - H00005152-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human PDE9A His tag protein - orb84215 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human PDE9A His GST tag protein - orb84216 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Insect Species Human

PDE9A Blocking Peptide - 33R-8356 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDE9A - H00005152-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

PDE9A - H00005152-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PDE9A - H00005152-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PDE9A - H00005152-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PDE9A - H00005152-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PDE9A Control Peptide - AP10254CP-N from Acris Antibodies Category Peptide Prices $255.00 Sizes 100 µg

Phosphodiesterase 9A (PDE9A), Human - 20-9107 from ARP American Research Products Category Protein Prices $555.00 Sizes 50 µg Source E.coli Species Human

PDE9A fusion protein - ag3372 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PDE9A2, Active Human Recombinant Protein - GWB-15988D from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

Recombinant Human Phosphodiesterase 9A, GST-tagged - PDE9A-448H from Creative Biomart Category Protein Source Insect cells Species Human

Recombinant Human PDE9A, His tagged - PDE9A-1162H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human PDE9A, His & GST tagged - PDE9A-1163H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human PDE9A, His-tagged - PDE9A-550H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human PDE9A, His/GST-tagged - PDE9A-551H from Creative Biomart Category Protein Source Insect cells Species Human

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