Gene Symbol | CNIH3 |
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Entrez Gene | 149111 |
Alt Symbol | CNIH-3 |
Species | Human |
Gene Type | protein-coding |
Description | cornichon family AMPA receptor auxiliary protein 3 |
Other Description | cornichon homolog 3|protein cornichon homolog 3 |
Swissprots | Q8TBE1 |
Accessions | EAW69732 Q8TBE1 AF070524 AK096312 BAC04760 BC022780 AAH22780 HQ447327 ADQ31813 XM_005273075 XP_005273132 XM_011544101 XP_011542403 XM_011544102 XP_011542404 XM_011544103 XP_011542405 XM_011544104 XP_011542406 XM_011544105 XP_011542407 XM_011544106 XP_011542408 XM_011544107 XP_011542409 NM_152495 NP_689708 |
Function | Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. {ECO:0000269|PubMed:20805473}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). {ECO:0000250}. |
Tissue Specificity | Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). {ECO:0000269|PubMed:23103966}. |
CNIH3 CRISPR/Cas9 KO Plasmid (h) - sc-409376 from Santa Cruz Biotechnology
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CNIH3 HDR Plasmid (h) - sc-409376-HDR from Santa Cruz Biotechnology
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CNIH3 Double Nickase Plasmid (h) - sc-409376-NIC from Santa Cruz Biotechnology
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CNIH3 Double Nickase Plasmid (h2) - sc-409376-NIC-2 from Santa Cruz Biotechnology
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CNIH3 CRISPR Activation Plasmid (h) - sc-409376-ACT from Santa Cruz Biotechnology
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CNIH3 CRISPR Activation Plasmid (h2) - sc-409376-ACT-2 from Santa Cruz Biotechnology
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CNIH3 Lentiviral Activation Particles (h) - sc-409376-LAC from Santa Cruz Biotechnology
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CNIH3 Lentiviral Activation Particles (h2) - sc-409376-LAC-2 from Santa Cruz Biotechnology
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CNIH3 siRNA (h) - sc-78610 from Santa Cruz Biotechnology
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CNIH3 shRNA Plasmid (h) - sc-78610-SH from Santa Cruz Biotechnology
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CNIH3 shRNA (h) Lentiviral Particles - sc-78610-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU136381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6305 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6305 from Sigma-Aldrich
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CNIH3 siRNA (Human) - CRJ5608 from Cohesion Biosciences
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CNIH3 RNAi - H00149111-R01 from Novus Biologicals
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CNIH3 - MBS8225598 from MyBioSource
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shRNA set against Human CNIH3 (NM_152495.1) - SHH266249 from Creative biogene
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Human CNIH3 siRNA - orb276109 from Biorbyt
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CNIH3 shRNA Plasmid (Human) - CHJ5608 from Cohesion Biosciences
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CNIH3 miRNA 3'UTR clone - MiUTR3H-14483 from Creative biogene
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