Gene Symbol | CD2 |
---|---|
Entrez Gene | 914 |
Alt Symbol | LFA-2, SRBC, T11 |
Species | Human |
Gene Type | protein-coding |
Description | CD2 molecule |
Other Description | CD2 antigen (p50), sheep red blood cell receptor|LFA-3 receptor|T-cell surface antigen CD2|T-cell surface antigen T11/Leu-5|erythrocyte receptor|lymphocyte-function antigen-2|rosette receptor |
Swissprots | Q96TE5 P06729 |
Accessions | AAA53095 CAA30721 CAJ86523 CBX51829 EAW56661 P06729 AK127925 AK223393 BAD97113 AK301154 BAG62744 AK303367 BAG64425 AK310676 AK313614 BAG36377 BC033583 AAH33583 DQ890953 ABM81879 DQ894115 ABM85041 M14362 AAA35571 M16336 AAA51946 M16445 AAA51738 XM_005271320 XP_005271377 NM_001767 NP_001758 |
Function | CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Hematopoietic cell lineage, Cell adhesion molecules (CAMs) |