Gene Symbol | CD2 |
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Entrez Gene | 914 |
Alt Symbol | LFA-2, SRBC, T11 |
Species | Human |
Gene Type | protein-coding |
Description | CD2 molecule |
Other Description | CD2 antigen (p50), sheep red blood cell receptor|LFA-3 receptor|T-cell surface antigen CD2|T-cell surface antigen T11/Leu-5|erythrocyte receptor|lymphocyte-function antigen-2|rosette receptor |
Swissprots | Q96TE5 P06729 |
Accessions | AAA53095 CAA30721 CAJ86523 CBX51829 EAW56661 P06729 AK127925 AK223393 BAD97113 AK301154 BAG62744 AK303367 BAG64425 AK310676 AK313614 BAG36377 BC033583 AAH33583 DQ890953 ABM81879 DQ894115 ABM85041 M14362 AAA35571 M16336 AAA51946 M16445 AAA51738 XM_005271320 XP_005271377 NM_001767 NP_001758 |
Function | CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Hematopoietic cell lineage, Cell adhesion molecules (CAMs) |
CD2 CRISPR/Cas9 KO Plasmid (h) - sc-402105 from Santa Cruz Biotechnology
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CD2 HDR Plasmid (h) - sc-402105-HDR from Santa Cruz Biotechnology
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CD2 Double Nickase Plasmid (h) - sc-402105-NIC from Santa Cruz Biotechnology
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CD2 Double Nickase Plasmid (h2) - sc-402105-NIC-2 from Santa Cruz Biotechnology
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CD2 CRISPR Activation Plasmid (h) - sc-402105-ACT from Santa Cruz Biotechnology
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CD2 CRISPR Activation Plasmid (h2) - sc-402105-ACT-2 from Santa Cruz Biotechnology
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CD2 Lentiviral Activation Particles (h) - sc-402105-LAC from Santa Cruz Biotechnology
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CD2 Lentiviral Activation Particles (h2) - sc-402105-LAC-2 from Santa Cruz Biotechnology
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CD2 siRNA (h) - sc-29970 from Santa Cruz Biotechnology
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CD2 shRNA Plasmid (h) - sc-29970-SH from Santa Cruz Biotechnology
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CD2 shRNA (h) Lentiviral Particles - sc-29970-V from Santa Cruz Biotechnology
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CD2 RNAi - H00000914-R02 from Novus Biologicals
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MISSION® esiRNA - EHU037711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5694 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5694 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03779 from Sigma-Aldrich
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CD2 siRNA (Human) - CRH0643 from Cohesion Biosciences
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CD2 - MBS8217917 from MyBioSource
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shRNA set against Human CD2 (NM_001767.3) - SHH258621 from Creative biogene
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shRNA set against Human CD2(NM_001767.3) - SHG155413 from Creative biogene
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Human CD2 siRNA - orb261145 from Biorbyt
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CD2 shRNA Plasmid (Human) - CHH0643 from Cohesion Biosciences
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CD2 miRNA 3'UTR clone - MiUTR1H-01848 from Creative biogene
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