Gene Symbol | CRADD |
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Entrez Gene | 8738 |
Alt Symbol | MRT34, RAIDD |
Species | Human |
Gene Type | protein-coding |
Description | CASP2 and RIPK1 domain containing adaptor with death domain |
Other Description | RIP-associated ICH1/CED3-homologous protein with death domain|RIP-associated protein with a death domain|caspase and RIP adaptor with death domain|death adaptor molecule RAIDD|death domain-containing protein CRADD |
Swissprots | B7Z2Q5 P78560 |
Accessions | EAW97497 P78560 AA150833 AB451280 BAG70094 AB451412 BAG70226 AI791547 AK294986 BAH11941 AK296225 BAG58948 AK314861 BAG37377 BC017042 AAH17042 BC037905 AAH37905 BT009837 AAP88839 CD696130 CR407643 CAG28571 DQ891780 ABM82706 DQ894964 ABM85890 U79115 AAB42217 U84388 AAC50952 XM_005269211 XP_005269268 NM_003805 NP_003796 |
Function | Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. |
Human RAIDD full length protein - ab172821 from Abcam
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Human RAIDD full length protein - ab78880 from Abcam
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Human RAIDD peptide - ab8460 from Abcam
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CRADD / RAIDD Antibody Blocking Peptide - LS-E6168 from LifeSpan Bioscience
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CRADD / RAIDD Antibody Blocking Peptide - LS-E29839 from LifeSpan Bioscience
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CRADD / RAIDD Antibody Blocking Peptide - LS-E29840 from LifeSpan Bioscience
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RAIDD/CRADD Recombinant Protein - H00008738-P01 from Novus Biologicals
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RAIDD/CRADD Recombinant Protein - H00008738-P02 from Novus Biologicals
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Recombinant Human RAIDD/CRADD Protein - NBC1-18519 from Novus Biologicals
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RAIDD/CRADD Blocking Peptide - NBP1-77048PEP from Novus Biologicals
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RAIDD/CRADD Blocking Peptide - NBP1-77061PEP from Novus Biologicals
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CRADD-Antibody-Center-Blocking-Peptide - BP18802c from Abgent, a WuXi AppTec company
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RAIDD peptide - GTX28460 from GeneTex
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RAIDD peptide - GTX28461 from GeneTex
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CRADD Protein (OPPA01736) - OPPA01736 from Aviva Systems Biology
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Human CRADD R protein - orb163501 from Biorbyt
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Human CRADD His tag protein - orb84537 from Biorbyt
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Human Caspase and RIP Adapter with Death Domain protein - orb81048 from Biorbyt
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Human CRADD protein - orb244128 from Biorbyt
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CRADD protein (His tag) - 80R-1078 from Fitzgerald
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RAIDD Blocking Peptide - 33R-10605 from Fitzgerald
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Human CRADD Protein - abx065745 from Abbexa
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RAIDD Blocking Peptide - abx063511 from Abbexa
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RAIDD (1-199, His-tag) - AR09013PU-L from Acris Antibodies
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RAIDD (1-199, His-tag) - AR09013PU-N from Acris Antibodies
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