| Gene Symbol |
PKN3
|
| Entrez Gene |
29941
|
| Alt Symbol |
UTDP4-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein kinase N3
|
| Other Description |
protein kinase PKN-beta|protein-kinase C-related kinase 3|serine/threonine-protein kinase N3
|
| Swissprots |
Q6P5Z2 Q9UM03
|
| Accessions |
EAW87824 EAW87825 Q6P5Z2 AB019692 BAA85625 AI741632 AK097535 BC023327 BC032794 AAH32794 BC041581 BC062558 AAH62558 BQ009753 BU854923 CB987960 EU831416 ACE87103 EU831509 ACE86428 XM_005251946 XP_005252003 XM_006717080 XP_006717143 XM_006717082 XP_006717145 XM_011518595 XP_011516897 XM_011518596 XP_011516898 XM_011518597 XP_011516899 XM_011518598 XP_011516900 NM_013355 NP_037487
|
| Function |
Contributes to invasiveness in malignant prostate cancer. {ECO:0000269|PubMed:15282551}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:10441506}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10441506}. Note=Nuclear and perinuclear Golgi region.
|
| Tissue Specificity |
Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues. {ECO:0000269|PubMed:10441506}.
|
| Top Pathways |
Salmonella infection, PI3K-Akt signaling pathway
|
![Western Blot: PKN3 Overexpression Lysate (Adult Normal) [NBL1-14464] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PKN3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7202_PKN3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14464-img0002.jpg)