KLK3
| Gene Symbol | KLK3 |
|---|---|
| Entrez Gene | 354 |
| Alt Symbol | APS, KLK2A1, PSA, hK3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | kallikrein-related peptidase 3 |
| Other Description | P-30 antigen|gamma-seminoprotein|kallikrein-3|prostate specific antigen|prostate-specific antigen|semenogelase|seminin |
| Swissprots | P07288 Q8IXI4 Q16272 G3XAE3 Q86TG8 C9JXH3 Q15096 G3V0H4 |
| Accessions | AAA60192 AAA60193 AAG33355 CAA32123 CAA32124 CAA32126 CAA32127 CAA32915 CAB46487 EAW71922 EAW71923 EAW71924 EAW71925 EAW71926 EAW71927 EAW71928 EAW71929 EAW71930 EAW71931 EAW71932 EAW71933 EAW71934 EAW71935 EAW71936 P07288 AF335477 AAL73204 AF335478 AAL73205 AJ310937 CAC41631 AJ310938 CAC41632 AJ459782 CAD30844 AJ459783 CAD30845 AJ459784 CAD30846 AJ512346 CAD54617 AK312933 BAG35776 AX772834 CAE06266 BC005307 AAH05307 BC050595 AAH50595 BC056665 AAH56665 BF679511 BQ932072 BT019862 AAV38665 DQ641251 DQ890670 ABM81596 DQ893851 ABM84777 M21895 AAA59995 M21896 AAA59996 M21897 AAA59997 M26663 AAA58802 S75755 AAD14185 U17040 AAA56764 X05332 CAA28947 X07730 X75682 XM_011526923 XP_011525225 XM_011526924 XP_011525226 XR_935817 NM_001030047 NP_001025218 NM_001030048 NP_001025219 NM_001648 NP_001639 NM_001030049 NM_001030050 |
| Function | Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. |
| Subcellular Location | Secreted. |
| Top Pathways | Prostate cancer |
PSA CRISPR/Cas9 KO Plasmid (h) - sc-400448 from Santa Cruz Biotechnology
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PSA HDR Plasmid (h) - sc-400448-HDR from Santa Cruz Biotechnology
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PSA Double Nickase Plasmid (h) - sc-400448-NIC from Santa Cruz Biotechnology
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PSA Double Nickase Plasmid (h2) - sc-400448-NIC-2 from Santa Cruz Biotechnology
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PSA CRISPR Activation Plasmid (h) - sc-400448-ACT from Santa Cruz Biotechnology
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PSA CRISPR Activation Plasmid (h2) - sc-400448-ACT-2 from Santa Cruz Biotechnology
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PSA Lentiviral Activation Particles (h) - sc-400448-LAC from Santa Cruz Biotechnology
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PSA Lentiviral Activation Particles (h2) - sc-400448-LAC-2 from Santa Cruz Biotechnology
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PSA siRNA (h) - sc-29458 from Santa Cruz Biotechnology
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PSA shRNA Plasmid (h) - sc-29458-SH from Santa Cruz Biotechnology
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PSA shRNA (h) Lentiviral Particles - sc-29458-V from Santa Cruz Biotechnology
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Kallikrein 3/PSA RNAi - H00000354-R01 from Novus Biologicals
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Kallikrein 3/PSA RNAi - H00000354-R03 from Novus Biologicals
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Kallikrein 3/PSA RNAi - H00000354-R02 from Novus Biologicals
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Kallikrein 3/PSA RNAi - H00000354-R05 from Novus Biologicals
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MISSION® esiRNA - EHU156951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11311 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08330 from Sigma-Aldrich
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KLK3 siRNA (Human) - CRH0250 from Cohesion Biosciences
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Kallikrein 3/PSA RNAi - H00000354-R04 from Novus Biologicals
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shRNA set against Human KLK3(NM_001030050.1) - SHH138233 from Creative biogene
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shRNA set against Human KLK3(NM_001030047.1) - SHH138251 from Creative biogene
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shRNA set against Human KLK3(NM_001030048.1) - SHH138287 from Creative biogene
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shRNA set against Human KLK3(NM_001648.2) - SHH138305 from Creative biogene
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