| Gene Symbol |
TCERG1
|
| Entrez Gene |
10915
|
| Alt Symbol |
CA150, TAF2S, Urn1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription elongation regulator 1
|
| Other Description |
TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD|TATA box-binding protein-associated factor 2S|co-activator of 150 kDa|transcription factor CA150
|
| Swissprots |
O14776 Q2NKN2 Q59EA1
|
| Accessions |
EAW61840 EAW61841 EAW61842 O14776 AB209910 BAD93147 AF017789 AAB80727 AK074511 AK126455 AK304319 BAH14157 AU125627 BC006109 BC014151 BC015864 BC035150 BC062351 BC111727 AAI11728 DA034307 DA737038 XM_005268365 XP_005268422 XM_011537545 XP_011535847 XM_011537546 XP_011535848 XM_011537547 XP_011535849 XM_011537548 XP_011535850 XM_011537549 XP_011535851 XR_944306 XR_944307 NM_001040006 NP_001035095 NM_006706 NP_006697
|
| Function |
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. {ECO:0000269|PubMed:11604498, ECO:0000269|PubMed:9315662}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:10908677, ECO:0000269|PubMed:15485897, ECO:0000269|PubMed:9315662}.
|
| Tissue Specificity |
Detected in brain neurons. {ECO:0000269|PubMed:11172033}.
|
| Top Pathways |
Spliceosome
|