Gene Symbol | TCERG1 |
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Entrez Gene | 10915 |
Alt Symbol | CA150, TAF2S, Urn1 |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation regulator 1 |
Other Description | TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD|TATA box-binding protein-associated factor 2S|co-activator of 150 kDa|transcription factor CA150 |
Swissprots | O14776 Q2NKN2 Q59EA1 |
Accessions | EAW61840 EAW61841 EAW61842 O14776 AB209910 BAD93147 AF017789 AAB80727 AK074511 AK126455 AK304319 BAH14157 AU125627 BC006109 BC014151 BC015864 BC035150 BC062351 BC111727 AAI11728 DA034307 DA737038 XM_005268365 XP_005268422 XM_011537545 XP_011535847 XM_011537546 XP_011535848 XM_011537547 XP_011535849 XM_011537548 XP_011535850 XM_011537549 XP_011535851 XR_944306 XR_944307 NM_001040006 NP_001035095 NM_006706 NP_006697 |
Function | Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. {ECO:0000269|PubMed:11604498, ECO:0000269|PubMed:9315662}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10908677, ECO:0000269|PubMed:15485897, ECO:0000269|PubMed:9315662}. |
Tissue Specificity | Detected in brain neurons. {ECO:0000269|PubMed:11172033}. |
Top Pathways | Spliceosome |
CA150 CRISPR/Cas9 KO Plasmid (h) - sc-409124 from Santa Cruz Biotechnology
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CA150 HDR Plasmid (h) - sc-409124-HDR from Santa Cruz Biotechnology
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CA150 Double Nickase Plasmid (h) - sc-409124-NIC from Santa Cruz Biotechnology
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CA150 Double Nickase Plasmid (h2) - sc-409124-NIC-2 from Santa Cruz Biotechnology
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CA150 CRISPR Activation Plasmid (h) - sc-409124-ACT from Santa Cruz Biotechnology
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CA150 CRISPR Activation Plasmid (h2) - sc-409124-ACT-2 from Santa Cruz Biotechnology
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CA150 Lentiviral Activation Particles (h) - sc-409124-LAC from Santa Cruz Biotechnology
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CA150 Lentiviral Activation Particles (h2) - sc-409124-LAC-2 from Santa Cruz Biotechnology
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CA150 siRNA (h) - sc-37728 from Santa Cruz Biotechnology
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CA150 shRNA Plasmid (h) - sc-37728-SH from Santa Cruz Biotechnology
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CA150 shRNA (h) Lentiviral Particles - sc-37728-V from Santa Cruz Biotechnology
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TCERG1 RNAi - H00010915-R01 from Novus Biologicals
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MISSION® esiRNA - EHU038791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21136 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21136 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06820 from Sigma-Aldrich
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TCERG1 siRNA (Human) - CRH7443 from Cohesion Biosciences
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TCERG1 - MBS8202151 from MyBioSource
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shRNA set against Human TCERG1 (NM_006706.3) - SHH424716 from Creative biogene
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shRNA set against Human TCERG1(NM_006706.3) - SHL061338 from Creative biogene
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shRNA set against Human TCERG1(NM_001040006.1) - SHL061614 from Creative biogene
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Human TCERG1 siRNA - orb267945 from Biorbyt
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TCERG1 shRNA Plasmid (Human) - CHH7443 from Cohesion Biosciences
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TCERG1 miRNA 3'UTR clone - MiUTR1H-10265 from Creative biogene
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TCERG1 miRNA 3'UTR clone - MiUTR1H-10266 from Creative biogene
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