| Gene Symbol |
SMDT1
|
| Entrez Gene |
91689
|
| Alt Symbol |
C22orf32, DDDD, EMRE, dJ186O1.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
single-pass membrane protein with aspartate-rich tail 1
|
| Other Description |
UPF0466 protein C22orf32, mitochondrial|essential MCU regulator, mitochondrial|single-pass membrane protein with aspartate-rich tail 1, mitochondrial
|
| Swissprots |
Q9H4I9 Q8TAB9 B2R5D1
|
| Accessions |
EAW60488 Q9H4I9 AK095636 AK312142 BAG35078 AL449243 CAC15000 BC024237 AAH24237 BI754670 CR456453 CAG30339 XM_011530509 XP_011528811 XM_011547037 XP_011545339 XM_011547542 XP_011545844 XM_011547754 XP_011546056 NM_033318 NP_201575
|
| Function |
Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria. Required to bridge the calcium- sensing proteins MICU1 and MICU2 with the calcium-conducting subunit MCU. {ECO:0000269|PubMed:24231807}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:24231807}; Single-pass membrane protein {ECO:0000269|PubMed:24231807}.
|