Gene Symbol | TEP1 |
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Entrez Gene | 7011 |
Alt Symbol | TLP1, TP1, TROVE1, VAULT2, p240 |
Species | Human |
Gene Type | protein-coding |
Description | telomerase-associated protein 1 |
Other Description | TROVE domain family, member 1|p80 telomerase homolog|telomerase protein 1|telomerase protein component 1 |
Swissprots | A0AUV9 Q99973 |
Accessions | CCQ43385 EAW66475 Q99973 AB209669 BAD92906 AK303307 BAG64378 BC126107 AAI26108 BC143812 BC143815 BX640983 CAE45993 U86136 AAC51107 XM_005268027 XP_005268084 XM_011537110 XP_011535412 XM_011537111 XP_011535413 XR_245720 XR_429328 NM_007110 NP_009041 |
Function | Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. Chromosome, telomere. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9020079}. |
TP1 (B-1) - sc-166620 from Santa Cruz Biotechnology
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TP1 (C-20)-R - sc-6370-R from Santa Cruz Biotechnology
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TP1 (H-300) - sc-13052 from Santa Cruz Biotechnology
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TP1 (N-19) - sc-6372 from Santa Cruz Biotechnology
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Anti-TEP1 antibody - ab64189 from Abcam
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Anti-TEP1 antibody - ab203248 from Abcam
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Anti-TP1 / TEP1 Antibody (N-Terminus) IHC-plus⢠- LS-B597 from LifeSpan Bioscience
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Anti-TP1 / TEP1 Antibody (Internal) - LS-C10512 from LifeSpan Bioscience
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Anti-TP1 / TEP1 Antibody (aa171-220) - LS-C119229 from LifeSpan Bioscience
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Anti-TP1 / TEP1 Antibody (aa2368-2627) - LS-C314541 from LifeSpan Bioscience
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TEP1 Antibody - NBP1-77285 from Novus Biologicals
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TEP1 Antibody - NBP1-03224 from Novus Biologicals
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TEP1 Antibody - NBP1-82446 from Novus Biologicals
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TEP1 Antibody - H00007011-A01 from Novus Biologicals
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TEP1 Polyclonal Antibody - bs-1908R from Bioss
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Anti-TEP1 antibody produced in rabbit - HPA029206 from Sigma-Aldrich
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Anti-TP1 antibody produced in rabbit - PRS2345 from Sigma-Aldrich
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Anti-DOK1 antibody produced in rabbit - PRS1107 from Sigma-Aldrich
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TEP1 Antibody (OAAF02639) - OAAF02639 from Aviva Systems Biology
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TEP1 antibody - orb11473 from Biorbyt
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TP1 antibody - orb74430 from Biorbyt
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TEP1 Antibody (OABF00865) - OABF00865 from Aviva Systems Biology
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TLP1 antibody - 70R-33173 from Fitzgerald
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TEP1 antibody - orb13708 from Biorbyt
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TEP1 antibody - orb193942 from Biorbyt
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