| Gene Symbol |
TEP1
|
| Entrez Gene |
7011
|
| Alt Symbol |
TLP1, TP1, TROVE1, VAULT2, p240
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
telomerase-associated protein 1
|
| Other Description |
TROVE domain family, member 1|p80 telomerase homolog|telomerase protein 1|telomerase protein component 1
|
| Swissprots |
A0AUV9 Q99973
|
| Accessions |
CCQ43385 EAW66475 Q99973 AB209669 BAD92906 AK303307 BAG64378 BC126107 AAI26108 BC143812 BC143815 BX640983 CAE45993 U86136 AAC51107 XM_005268027 XP_005268084 XM_011537110 XP_011535412 XM_011537111 XP_011535413 XR_245720 XR_429328 NM_007110 NP_009041
|
| Function |
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000305}. Chromosome, telomere.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:9020079}.
|