| Gene Symbol |
GPR26
|
| Entrez Gene |
2849
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor 26
|
| Other Description |
G-protein coupled receptor 26
|
| Swissprots |
Q8NDV2 Q2M2E2
|
| Accessions |
EAW49281 EAW49282 Q8NDV2 AI076749 AJ505757 CAD44281 AK091093 AL713636 BC112011 AAI12012 BC113462 AAI13463 NM_153442 NP_703143
|
| Function |
Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. {ECO:0000269|PubMed:17363172}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma. {ECO:0000269|PubMed:17363172, ECO:0000269|PubMed:18037267}.
|