Gene Symbol | GPR26 |
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Entrez Gene | 2849 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 26 |
Other Description | G-protein coupled receptor 26 |
Swissprots | Q8NDV2 Q2M2E2 |
Accessions | EAW49281 EAW49282 Q8NDV2 AI076749 AJ505757 CAD44281 AK091093 AL713636 BC112011 AAI12012 BC113462 AAI13463 NM_153442 NP_703143 |
Function | Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. {ECO:0000269|PubMed:17363172}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma. {ECO:0000269|PubMed:17363172, ECO:0000269|PubMed:18037267}. |
GPR26 CRISPR/Cas9 KO Plasmid (h) - sc-407710 from Santa Cruz Biotechnology
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GPR26 HDR Plasmid (h) - sc-407710-HDR from Santa Cruz Biotechnology
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GPR26 Double Nickase Plasmid (h) - sc-407710-NIC from Santa Cruz Biotechnology
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GPR26 Double Nickase Plasmid (h2) - sc-407710-NIC-2 from Santa Cruz Biotechnology
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GPR26 CRISPR Activation Plasmid (h) - sc-407710-ACT from Santa Cruz Biotechnology
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GPR26 CRISPR Activation Plasmid (h2) - sc-407710-ACT-2 from Santa Cruz Biotechnology
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GPR26 Lentiviral Activation Particles (h) - sc-407710-LAC from Santa Cruz Biotechnology
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GPR26 Lentiviral Activation Particles (h2) - sc-407710-LAC-2 from Santa Cruz Biotechnology
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GPR26 siRNA (h) - sc-90365 from Santa Cruz Biotechnology
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GPR26 shRNA Plasmid (h) - sc-90365-SH from Santa Cruz Biotechnology
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GPR26 shRNA (h) Lentiviral Particles - sc-90365-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU035751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9596 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9596 from Sigma-Aldrich
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GPR26 siRNA (Human) - CRH1912 from Cohesion Biosciences
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GPR26 - MBS8225883 from MyBioSource
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shRNA set against Human GPR26 (NM_153442.3) - SHH306722 from Creative biogene
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Human GPR26 siRNA - orb262414 from Biorbyt
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GPR26 shRNA Plasmid (Human) - CHH1912 from Cohesion Biosciences
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