| Gene Symbol |
RLN2
|
| Entrez Gene |
6019
|
| Alt Symbol |
H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
relaxin 2
|
| Other Description |
H2-preprorelaxin|prorelaxin H2|relaxin, ovarian, of pregnancy
|
| Swissprots |
Q9UCX3 Q99936 Q9UQJ2 P04090 A0AVM0
|
| Accessions |
AAD21961 EAW58770 EAW58771 P04090 A06925 CAA00602 A17315 CAA01324 AA935560 AF057706 AI033912 BC126415 AAI26416 BC126419 AAI26420 BG206251 BX094853 HQ258745 ADR83496 X00948 CAA25460 XM_011518003 XP_011516305 NM_005059 NP_005050 NM_134441 NP_604390
|
| Function |
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary. {ECO:0000269|PubMed:6548702, ECO:0000269|PubMed:8735594}.
|