Gene Symbol | RLN2 |
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Entrez Gene | 6019 |
Alt Symbol | H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2 |
Species | Human |
Gene Type | protein-coding |
Description | relaxin 2 |
Other Description | H2-preprorelaxin|prorelaxin H2|relaxin, ovarian, of pregnancy |
Swissprots | Q9UCX3 Q99936 Q9UQJ2 P04090 A0AVM0 |
Accessions | AAD21961 EAW58770 EAW58771 P04090 A06925 CAA00602 A17315 CAA01324 AA935560 AF057706 AI033912 BC126415 AAI26416 BC126419 AAI26420 BG206251 BX094853 HQ258745 ADR83496 X00948 CAA25460 XM_011518003 XP_011516305 NM_005059 NP_005050 NM_134441 NP_604390 |
Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary. {ECO:0000269|PubMed:6548702, ECO:0000269|PubMed:8735594}. |
Relaxin 2 CRISPR/Cas9 KO Plasmid (h) - sc-404671 from Santa Cruz Biotechnology
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Relaxin 2 HDR Plasmid (h) - sc-404671-HDR from Santa Cruz Biotechnology
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Relaxin 2 Double Nickase Plasmid (h) - sc-404671-NIC from Santa Cruz Biotechnology
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Relaxin 2 Double Nickase Plasmid (h2) - sc-404671-NIC-2 from Santa Cruz Biotechnology
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Relaxin 2 CRISPR Activation Plasmid (h) - sc-404671-ACT from Santa Cruz Biotechnology
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Relaxin 2 CRISPR Activation Plasmid (h2) - sc-404671-ACT-2 from Santa Cruz Biotechnology
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Relaxin 2 Lentiviral Activation Particles (h) - sc-404671-LAC from Santa Cruz Biotechnology
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Relaxin 2 Lentiviral Activation Particles (h2) - sc-404671-LAC-2 from Santa Cruz Biotechnology
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Relaxin 2 siRNA (h) - sc-63336 from Santa Cruz Biotechnology
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Relaxin 2 shRNA Plasmid (h) - sc-63336-SH from Santa Cruz Biotechnology
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Relaxin 2 shRNA (h) Lentiviral Particles - sc-63336-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU100381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18308 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18308 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04961 from Sigma-Aldrich
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RLN2 siRNA (Human) - CRH4085 from Cohesion Biosciences
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RLN2 - MBS8222475 from MyBioSource
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shRNA set against Human RLN2 (NM_005059.2) - SHH396148 from Creative biogene
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shRNA set against Human RLN2(NM_134441.1) - SHR183354 from Creative biogene
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shRNA set against Human RLN2(NM_005059.2) - SHR183432 from Creative biogene
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Human RLN2 siRNA - orb264587 from Biorbyt
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RLN2 shRNA Plasmid (Human) - CHH4085 from Cohesion Biosciences
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RLN2 miRNA 3'UTR clone - MiUTR1H-08842 from Creative biogene
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RLN2 miRNA 3'UTR clone - MiUTR1H-08843 from Creative biogene
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