DDX46

Gene Symbol	DDX46
Entrez Gene	9879
Alt Symbol	PRPF5, Prp5
Species	Human
Gene Type	protein-coding
Description	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
Other Description	DEAD box protein 46\|PRP5 homolog\|Prp5-like DEAD-box protein\|RNA helicase\|probable ATP-dependent RNA helicase DDX46
Swissprots	Q96EI0 Q7L014 Q9Y658 O94894
Accessions	EAW62238 EAW62239 EAW62240 EAW62241 EAW62242 Q7L014 AB018344 BAA34521 AF106680 AAD43033 AI003503 AK058058 AK126011 AK291788 BAF84477 BC012304 AAH12304 BC030755 BC105598 AAI05599 BF244218 BK000565 DAA00076 BU608108 BX647426 CA314463 CB052404 XM_011543757 XP_011542059 XM_011543758 XP_011542060 XR_948313 XR_948314 NM_001300860 NP_001287789 NM_014829 NP_055644 NR_125341
Function	Plays an essential role in splicing, either prior to, or during splicing A complex formation. {ECO:0000269\|PubMed:12234937}.
Subcellular Location	Nucleus speckle {ECO:0000269\|PubMed:12234937}. Nucleus, Cajal body {ECO:0000269\|PubMed:12234937}. Note=Present in Cajal bodies (CBs) and nuclear speckles.
Top Pathways	Spliceosome

DDX46 (B-6) - sc-514071 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

DDX46 (B-6): sc-514071. Western blot analysis of DDX46 expression in non-transfected: sc-117752 (A) and mouse DDX46 transfected: sc-119722 (B) 293T whole cell lysates.

DDX46 (C-17) - sc-68304 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

DDX46 (C-17): sc-68304. Western blot analysis of DDX46 expression in non-transfected: sc-117752 (A) and truncated mouse DDX46 transfected: sc-119722 (B) 293T whole cell lysates.

DDX46 (T-17) - sc-68307 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

DDX46 (T-17): sc-68307. Western blot analysis of DDX46 expression in non-transfected: sc-117752 (A) and truncated mouse DDX46 transfected: sc-119722 (B) 293T whole cell lysates.

Anti-DDX46 antibody - ab72083 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma (left) and mouse teratoma (right) tissues labelling DDX46 with ab72083 at 1/200 (1µg/ml). Detection: DAB.

Anti-DDX46 antibody - ab84463 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ab84463, at 1/250 dilution, staining DDX46 in formalin-fixed, paraffin-embedded human breast carcinoma by Immunohistochemistry, using DAB detection.

Anti-DDX46 antibody - C-terminal - ab155829 from Abcam

Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-DDX46 antibody - C-terminal (ab155829) at 1/3000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : HeLa whole cell lysateLane 4 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-DDX46 Antibody (aa300-350) - LS-C64614 from LifeSpan Bioscience

Prices	$545.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DDX46 Antibody (C-Terminus) - LS-C31470 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DDX46 Antibody (aa300-350) - LS-C287881 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human and Mouse DDX46 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-DDX46 used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Anti-DDX46 Antibody (C-Terminus) - LS-C287883 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-DDX46 Antibody (aa900-949) - LS-C110157 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DDX46 antibody LS-C110157 Western blot of MCF7 cell lysate.

Anti-DDX46 Antibody (C-Terminus) - LS-C286486 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Mouse DDX46 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-DDX46 used at a dilution of 1:250.

Anti-DDX46 Antibody (C-Terminus) - LS-C64612 from LifeSpan Bioscience

Prices	$545.00
Sizes	20 µg
Host	Rabbit
Clonality	Polyclonal

DDX46 Antibody - NBP1-83565 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DDX46 Antibody - NB100-57490 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DDX46 Antibody [NB100-57490] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. NB100-57490 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. DDX46 was also immunoprecipitated by rabbit anti-DDX46 antibody NB100-57489, which recognizes an upstream epitope.

DDX46 Antibody - NB100-57489 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: DDX46 Antibody [NB100-57489] - Human breast carcinoma (left) and mouse teratoma (right). Antibody used at a dilution of 1:1,000 (0.2ug/ml).

DDX46 Antibody - NBP2-16138 from Novus Biologicals

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DDX46 Antibody [NBP2-16138] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 5% SDS PAGE gel, diluted at 1:3000.

DDX46 Antibody - NBP2-16137 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DDX46 Antibody [NBP2-16137] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 7. 5% SDS PAGE gel, diluted at 1:1000.

Anti-DDX46 antibody produced in rabbit - HPA036554 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-DDX46: <B>Cat. No. HPA036554</B>: Immunohistochemical staining of human testis shows strong nuclear positivity in seminiferous tubules.

Anti-DDX46 antibody produced in rabbit - AV37717 from Sigma-Aldrich

Prices	$267.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV37717</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat

Anti-DDX46 antibody produced in rabbit - SAB2100555 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-DDX46: <B>Cat. No.SAB2100555</B>: DDX46 in MCF7 cell lysate with DDX46 antibody at 1.0 μg/mL.

DDX46 antibody - middle region (ARP36424_P050) - ARP36424_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DDX46 antibody - C-terminal region (ARP37717_T100) - ARP37717_T100 from Aviva Systems Biology

Prices	$229.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DDX46 antibody - GTX115309 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DDX46 antibody used in Western blot. GTX115309

DDX46 antibody [C2C3], C-term - GTX115308 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DDX46 antibody [C2C3], C-term used in Western blot. GTX115308

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