Gene Symbol | DDX46 |
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Entrez Gene | 9879 |
Alt Symbol | PRPF5, Prp5 |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
Other Description | DEAD box protein 46|PRP5 homolog|Prp5-like DEAD-box protein|RNA helicase|probable ATP-dependent RNA helicase DDX46 |
Swissprots | Q96EI0 Q7L014 Q9Y658 O94894 |
Accessions | EAW62238 EAW62239 EAW62240 EAW62241 EAW62242 Q7L014 AB018344 BAA34521 AF106680 AAD43033 AI003503 AK058058 AK126011 AK291788 BAF84477 BC012304 AAH12304 BC030755 BC105598 AAI05599 BF244218 BK000565 DAA00076 BU608108 BX647426 CA314463 CB052404 XM_011543757 XP_011542059 XM_011543758 XP_011542060 XR_948313 XR_948314 NM_001300860 NP_001287789 NM_014829 NP_055644 NR_125341 |
Function | Plays an essential role in splicing, either prior to, or during splicing A complex formation. {ECO:0000269|PubMed:12234937}. |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:12234937}. Nucleus, Cajal body {ECO:0000269|PubMed:12234937}. Note=Present in Cajal bodies (CBs) and nuclear speckles. |
Top Pathways | Spliceosome |
DDX46 CRISPR/Cas9 KO Plasmid (h) - sc-407298 from Santa Cruz Biotechnology
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DDX46 HDR Plasmid (h) - sc-407298-HDR from Santa Cruz Biotechnology
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DDX46 Double Nickase Plasmid (h) - sc-407298-NIC from Santa Cruz Biotechnology
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DDX46 Double Nickase Plasmid (h2) - sc-407298-NIC-2 from Santa Cruz Biotechnology
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DDX46 CRISPR Activation Plasmid (h) - sc-407298-ACT from Santa Cruz Biotechnology
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DDX46 CRISPR Activation Plasmid (h2) - sc-407298-ACT-2 from Santa Cruz Biotechnology
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DDX46 Lentiviral Activation Particles (h) - sc-407298-LAC from Santa Cruz Biotechnology
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DDX46 Lentiviral Activation Particles (h2) - sc-407298-LAC-2 from Santa Cruz Biotechnology
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DDX46 siRNA (h) - sc-62202 from Santa Cruz Biotechnology
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DDX46 shRNA Plasmid (h) - sc-62202-SH from Santa Cruz Biotechnology
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DDX46 shRNA (h) Lentiviral Particles - sc-62202-V from Santa Cruz Biotechnology
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DDX46 RNAi - H00009879-R02 from Novus Biologicals
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MISSION® esiRNA - EHU077891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7060 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7060 from Sigma-Aldrich
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DDX46 siRNA (Human) - CRH6626 from Cohesion Biosciences
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DDX46 - MBS8234398 from MyBioSource
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shRNA set against Human DDX46 (NM_014829.2) - SHH276053 from Creative biogene
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shRNA set against Human DDX46(NM_014829.2) - SHG226891 from Creative biogene
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DDX46 CRISPR/Cas9 KO Plasmid (h2) - sc-407298-KO-2 from Santa Cruz Biotechnology
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DDX46 HDR Plasmid (h2) - sc-407298-HDR-2 from Santa Cruz Biotechnology
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DDX46 shRNA Plasmid (Human) - CHH6626 from Cohesion Biosciences
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DDX46 miRNA 3'UTR clone - MiUTR1H-02735 from Creative biogene
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