| Gene Symbol |
TMED5
|
| Entrez Gene |
50999
|
| Alt Symbol |
CGI-100, p28
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane emp24 protein transport domain containing 5
|
| Other Description |
p24 family protein gamma-2|p24gamma2|transmembrane emp24 domain-containing protein 5
|
| Swissprots |
B2R703 Q9Y3A6 Q96AX8 D3DT38 B1AKT4
|
| Accessions |
EAW73081 EAW73082 Q9Y3A6 AF151858 AAD34095 AI436590 AK125882 AK293308 BAG56828 AK312787 BAG35650 AL080084 AY359039 AAQ89398 BC016365 AAH16365 BC016556 AAH16556 BC023274 BC038511 AAH38511 BC070051 AAH70051 BX642274 CA314982 CR936808 HQ447395 ADQ31881 NM_001167830 NP_001161302 NM_016040 NP_057124 NR_030761
|
| Function |
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle- mediated retrograde transport. {ECO:0000269|PubMed:19948005}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Note=Probably cycles between compartments of the early secretatory pathway.
|
