Gene Symbol | TMED5 |
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Entrez Gene | 50999 |
Alt Symbol | CGI-100, p28 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane emp24 protein transport domain containing 5 |
Other Description | p24 family protein gamma-2|p24gamma2|transmembrane emp24 domain-containing protein 5 |
Swissprots | B2R703 Q9Y3A6 Q96AX8 D3DT38 B1AKT4 |
Accessions | EAW73081 EAW73082 Q9Y3A6 AF151858 AAD34095 AI436590 AK125882 AK293308 BAG56828 AK312787 BAG35650 AL080084 AY359039 AAQ89398 BC016365 AAH16365 BC016556 AAH16556 BC023274 BC038511 AAH38511 BC070051 AAH70051 BX642274 CA314982 CR936808 HQ447395 ADQ31881 NM_001167830 NP_001161302 NM_016040 NP_057124 NR_030761 |
Function | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle- mediated retrograde transport. {ECO:0000269|PubMed:19948005}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Note=Probably cycles between compartments of the early secretatory pathway. |
TMED5 CRISPR/Cas9 KO Plasmid (h) - sc-409918 from Santa Cruz Biotechnology
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TMED5 HDR Plasmid (h) - sc-409918-HDR from Santa Cruz Biotechnology
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TMED5 Double Nickase Plasmid (h) - sc-409918-NIC from Santa Cruz Biotechnology
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TMED5 Double Nickase Plasmid (h2) - sc-409918-NIC-2 from Santa Cruz Biotechnology
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TMED5 CRISPR Activation Plasmid (h) - sc-409918-ACT from Santa Cruz Biotechnology
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TMED5 CRISPR Activation Plasmid (h2) - sc-409918-ACT-2 from Santa Cruz Biotechnology
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TMED5 Lentiviral Activation Particles (h) - sc-409918-LAC from Santa Cruz Biotechnology
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TMED5 Lentiviral Activation Particles (h2) - sc-409918-LAC-2 from Santa Cruz Biotechnology
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TMED5 siRNA (h) - sc-78724 from Santa Cruz Biotechnology
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TMED5 shRNA Plasmid (h) - sc-78724-SH from Santa Cruz Biotechnology
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TMED5 shRNA (h) Lentiviral Particles - sc-78724-V from Santa Cruz Biotechnology
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TMED5 RNAi - H00050999-R01 from Novus Biologicals
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MISSION® esiRNA - EHU034431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21457 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21457 from Sigma-Aldrich
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TMED5 siRNA (Human) - CRH9441 from Cohesion Biosciences
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TMED5 - MBS8218193 from MyBioSource
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shRNA set against Human TMED5 (NM_016040.4) - SHH428620 from Creative biogene
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Human TMED5 siRNA - orb269943 from Biorbyt
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TMED5 shRNA Plasmid (Human) - CHH9441 from Cohesion Biosciences
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TMED5 miRNA 3'UTR clone - MiUTR4H-TG09030 from Creative biogene
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