Gene Symbol |
CNTN4
|
Entrez Gene |
152330
|
Alt Symbol |
AXCAM, BIG-2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
contactin 4
|
Other Description |
axonal-associated cell adhesion molecule|brain-derived immunoglobulin superfamily protein 2|contactin-4|neural cell adhesion protein BIG-2
|
Swissprots |
Q8TC35 Q8IWV2 B2RAX3 Q8IX14
|
Accessions |
EAW63873 EAW63874 EAW63875 EAW63876 EAW63877 EAW63878 Q8IWV2 AF464063 AAN86141 AF549455 AAP05786 AI022097 AK057278 BAG51896 AK095729 BAG53116 AK097633 BAG53498 AK125460 AK314396 BAG37020 AY090737 AAM00025 BC013797 BC026119 AAH26119 DA063654 DA796385 DB457029 R42166 XM_006713004 XP_006713067 XM_011533425 XP_011531727 XM_011533426 XP_011531728 XM_011533427 XP_011531729 XM_011533428 XP_011531730 XM_011533429 XP_011531731 XM_011533430 XP_011531732 XM_011533431 XP_011531733 NM_001206955 NP_001193884 NM_001206956 NP_001193885 NM_175607 NP_783200 NM_175613 NP_783302 NM_175612
|
Function |
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
|
Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor. Secreted {ECO:0000250}.
|
Tissue Specificity |
Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex. {ECO:0000269|PubMed:11013081, ECO:0000269|PubMed:14571131}.
|