CNTN4

Gene Symbol	CNTN4
Entrez Gene	152330
Alt Symbol	AXCAM, BIG-2
Species	Human
Gene Type	protein-coding
Description	contactin 4
Other Description	axonal-associated cell adhesion molecule\|brain-derived immunoglobulin superfamily protein 2\|contactin-4\|neural cell adhesion protein BIG-2
Swissprots	Q8TC35 Q8IWV2 B2RAX3 Q8IX14
Accessions	EAW63873 EAW63874 EAW63875 EAW63876 EAW63877 EAW63878 Q8IWV2 AF464063 AAN86141 AF549455 AAP05786 AI022097 AK057278 BAG51896 AK095729 BAG53116 AK097633 BAG53498 AK125460 AK314396 BAG37020 AY090737 AAM00025 BC013797 BC026119 AAH26119 DA063654 DA796385 DB457029 R42166 XM_006713004 XP_006713067 XM_011533425 XP_011531727 XM_011533426 XP_011531728 XM_011533427 XP_011531729 XM_011533428 XP_011531730 XM_011533429 XP_011531731 XM_011533430 XP_011531732 XM_011533431 XP_011531733 NM_001206955 NP_001193884 NM_001206956 NP_001193885 NM_175607 NP_783200 NM_175613 NP_783302 NM_175612
Function	Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor. Secreted {ECO:0000250}.
Tissue Specificity	Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex. {ECO:0000269\|PubMed:11013081, ECO:0000269\|PubMed:14571131}.

Contactin 4 (H-43) - sc-68856 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Contactin 4 (S-17) - sc-68161 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Contactin 4 (Y-18) - sc-68162 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-CNTN4 antibody - ab93450 from Abcam

Prices	$242.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-CNTN4 antibody (ab93450) at 1 µg/mlLane 1 : Mouse Hippocampus Tissue LysateLane 2 : Rat Olfactory Bulb LysateLane 3 : E14 Mouse Embryo Brain Tissue LysateLane 4 : E16 Ms Embryo Brain Tissue Lysate Lane 5 : E18 Ms Embryo Brain Tissue LysateLane 6 : Brain (Mouse) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.Observed band size : 150 kDa (why is the actual band size different from the predicted?)Additional bands at : 56 kDa (possible isoform).Exposure time : 12 minutes

Anti-CNTN4 antibody - ab196605 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence analysis of A549 cells labeling CNTN4 using ab196605 at 1/100 dilution

Anti-CNTN4 antibody [EPR8735] - ab137107 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8735

All lanes : Anti-CNTN4 antibody [EPR8735] (ab137107) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human cerebellum lysateLane 3 : Mouse brain lysateLysates/proteins at 10 µg per lane.SecondaryHRP-labelled Goat anti-Rabbit at 1/2000 dilution

Anti-CNTN4 antibody [EPR8736] - ab131285 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8736

All lanes : Anti-CNTN4 antibody [EPR8736] (ab131285) at 1/1000 dilutionLane 1 : Fetal brain lysateLane 2 : Human cerebellum lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Contactin 4 + 6 antibody - ab104526 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-CNTN4 Antibody (aa19-999) - LS-C184209 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Sheep
Clonality	Polyclonal

Anti-CNTN4 Antibody (aa731-980, Biotin) - LS-C298228 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CNTN4 Antibody (aa731-980, FITC) - LS-C303908 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CNTN4 Antibody (aa800-899) - LS-C307012 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-CNTN4 Antibody (aa661-710) - LS-C119876 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence of A549 cells, using CNTN4 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CNTN4 Antibody (aa160-172) - LS-C186467 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

CNTN4 antibody (0.5 ug/ml) staining of Mouse Olfactory bulb (lanes1 and 3) and Cerebral cortex (lanes 2 and 4), comparing wild type (lanes 3 and 4) with KO mice (lanes 1 and 2). The last lane contains a lysate of HEK293 overexpressing Mouse Cntn4 (lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Data obtained from Gerrald Lodewijk and Peter Burbach, Rudolf Magnus Institute, Utrecht, Netherlands.

Anti-CNTN4 Antibody (aa731-980) - LS-C293521 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-ARFGEF2 / BIG2 Antibody (Leu1527) - LS-C177355 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IHC of BIG2 (L1527) pAb in paraffin-embedded human colon carcinoma tissue.

Anti-CNTN4 Antibody (Internal, clone EPR8736) - LS-C154582 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8736

IHC of paraffin-embedded human brain tissue using anti-CNTN4 / Contactin 4 antibody.

Contactin-4 Antibody [Unconjugated] - AF2205 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

Contactin-4 Antibody - NBP1-89970 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Contactin-4 Antibody [NBP1-89970] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)

Contactin-4 Antibody (296015) - MAB2205 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	296015

Contactin-4 Antibody - NB100-91207 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Contactin-4 Antibody (4B10) - H00152330-M06 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4B10

Immunocytochemistry/Immunofluorescence: Contactin-4 Antibody (4B10) [H00152330-M06] - Analysis of monoclonal antibody to CNTN4 on HeLa cell. Antibody concentration 10 ug/ml

Rabbit Anti-CNTN4/AXCAM Polyclonal Antibody - bs-11074R from Bioss

Prices	$245.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Rabbit Anti-CNTN4/AXCAM Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11074R-A350 from Bioss

Prices	$325.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Rabbit Anti-CNTN4/AXCAM Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11074R-A488 from Bioss

Prices	$325.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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