EPHA3

Gene Symbol	EPHA3
Entrez Gene	2042
Alt Symbol	EK4, ETK, ETK1, HEK, HEK4, TYRO4
Species	Human
Gene Type	protein-coding
Description	EPH receptor A3
Other Description	EPH-like kinase 4|TYRO4 protein tyrosine kinase|eph-like tyrosine kinase 1|ephrin type-A receptor 3|human embryo kinase 1|tyrosine-protein kinase receptor ETK1
Swissprots	Q9H2V4 P29320 Q9H2V3
Accessions	CAA01906 CAM91183 CAT16931 EAW68857 P29320 AF213459 AAG43576 AF213460 AAG43577 AK024352 AK291411 BAF84100 BC026247 BC063282 AAH63282 HM437236 ADN43067 M83941 AAA58633 XM_005264715 XP_005264772 XM_005264716 XP_005264773 NM_005233 NP_005224 NM_182644 NP_872585
Function	Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development. {ECO:0000269|PubMed:11870224}.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed. Highest level in placenta.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EPHA3 / EPH Receptor A3 ELISA Kit (Sandwich ELISA) - LS-F8444 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 0.313-20 ng/ml

Phosphotyrosine EPHA3 / Ephrin Type-A Receptor 3 ELISA Kit - RAB0944 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human EPHA3 ELISA Kit - abx151426 from Abbexa Category ELISA Kit Sensitivity 0.118 ng/ml Range 0.313 ng/ml - 20 ng/ml

Ephrin Type A Receptor 3, EPHA3, Human, ELISA Kit - E-EL-H1055 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Ephrin type-A receptor 3, EPHA3, Human, ELISA Kit - E1114h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Ephrin Type A Receptor 3, EPHA3, Rabbit, ELISA Kit - E-EL-RB0959 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ephrin Type A Receptor 3, EPHA3, Chicken, ELISA Kit - E-EL-Ch0205 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Ephrin Type A Receptor 3, EPHA3, Porcine, ELISA Kit - E-EL-P0538 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ephrin Type A Receptor 3, EPHA3, Guinea Pig, ELISA Kit - E-EL-GP0626 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Ephrin Type A Receptor 3, EPHA3, Monkey, ELISA Kit - E-EL-MK1569 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

EPH receptor A3, ELISA Kit - MBS9332305 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3, ELISA Kit - MBS077232 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3, ELISA Kit - MBS096176 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3, ELISA Kit - MBS088266 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3, ELISA Kit - MBS077532 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3, ELISA Kit - MBS050147 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3, ELISA Kit - MBS070395 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ephrin Type A Receptor 3 (EPHA3), ELISA Kit - MBS2023797 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.118ng/mL. Range 0.313-20ng/mL

Human EPHA3(Ephrin Type A Receptor 3) ELISA Kit - E-EL-H1055 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Human EPHA3 (Ephrin Type A Receptor 3) CLIA Kit - E-CL-H0708 from Elabscience Category CLIA Kit Sensitivity 37.50 pg/mL Range Average Recovery (%)

EPHA3, ELISA Kit - MBS2515264 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313--20ng/mL

EPHA3, ELISA Kit - MBS2503509 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

EPHA3, ELISA Kit - MBS2501479 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

EPHA3, ELISA Kit - MBS2514544 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125-8000pg/mL

EPHA3, ELISA Kit - MBS2513278 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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