| Gene Symbol |
GNGT1
|
| Entrez Gene |
2792
|
| Alt Symbol |
GNG1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
|
| Other Description |
guanine nucleotide-binding protein G(T) subunit gamma-T1|transducin gamma chain
|
| Swissprots |
Q16026 O43835 A4D1H2 Q08447 Q6LCP6 P63211
|
| Accessions |
AAB92386 AAB92387 AAD13931 AAS02021 EAL24139 EAW76805 EAW76806 P63211 AF493869 AAM12583 BC029367 AAH29367 CR456912 CAG33193 DQ892560 ABM83486 DQ895775 ABM86701 S62027 AAB26896 NM_021955 NP_068774
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Tissue Specificity |
Retinal rod outer segment.
|
| Top Pathways |
Glutamatergic synapse, Dopaminergic synapse, GABAergic synapse, Morphine addiction, PI3K-Akt signaling pathway
|